Analytical Instrumentation

Apr 02, 2012
Pharmaceutical Technology
By Pharmaceutical Technology Editors
New product reviews for April 2012.
Nov 01, 2011
Pharmaceutical Technology
By Pharmaceutical Technology Editors
The authors describe the benefits of nuclear magnetic resonance (NMR) compared with traditional monitoring techniques. They also discuss how NMR reaction monitoring provides a new process analytical technology tool for industry.
Feb 11, 2011
Pharmaceutical Technology Europe
By Pharmaceutical Technology Editors
The way in which a suspension nasal spray product interacts with the body depends not only on the droplet size of the delivered droplet, but also on the particle size of the suspended API.
Jul 02, 2010
Pharmaceutical Technology
Nanotechnology is an important area of drug and biomedical research, and advancing nano-analysis is crucial for its further development.
Feb 02, 2009
Pharmaceutical Technology
A new book inspires readers to seek ways to apply NMR spectroscopy to their own purposes.
Jan 08, 2009
ePT--the Electronic Newsletter of Pharmaceutical Technology
By Pharmaceutical Technology Editors
Michigan State University researchers have discovered a technique for viewing whole cells to gain an understanding of protein inclusion bodies.
Apr 10, 2008
ePT--the Electronic Newsletter of Pharmaceutical Technology
By Pharmaceutical Technology Editors
Combining atomic force microscopy and infrared spectroscopy, scientists at the University of Illinois have demonstrated a method for simultaneous structural and chemical characterization of samples at the femtogram (10-15g) level.
Dec 02, 2007
Pharmaceutical Technology
By Pharmaceutical Technology Editors
Industry and regulatory organizations agree that the current focus on product quality will play a major role in shaping pharmaceutical development in the future. Key to this assessment of quality are the methods and technologies in pharmaceutical analytical testing.
Sep 01, 2007
Pharmaceutical Technology Europe
A new Raman spectroscopic method to detect magnesium stearate in powder blends and tablets is described. High-volume pharmaceutical manufacturing requires the use of lubricants to facilitate tablet ejection from compressing machines. However, lubricants may also bring a number of undesired problems that have been widely documented in pharmaceutical scientific literature. New analytical methods are needed to understand lubrication and provide process knowledge in support of FDA's process analytical technology initiative. The detection of magnesium stearate in lactose, mannitol, corn starch and other commercially important excipients is reported. The Raman spectroscopic method has a detection limit of about 0.1% (w/w) based on the 2848 cm-1 band that corresponds to the symmetric stretch of the methylene group in magnesium stearate.
Feb 01, 2007
Pharmaceutical Technology Europe
Raman spectroscopy has become a commonly used technique for physicochemical analysis that possesses many advantages over other analytical techniques. It is a very attractive characterization tool, not least because it enables measurements in water. However, very few examples of its application in an aqueous environment exist in literature. This paper provides some recent applications of Raman spectroscopy in pharmaceutical material and process characterization when water is present.
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