Analytics

Mar 30, 2007
ePT--the Electronic Newsletter of Pharmaceutical Technology
By Pharmaceutical Technology Editors
Agawam, MA (Mar. 26)-Contract manufacturing and testing laboratory Microtest signed a manufacturing deal with Antisoma to produce AS1411, a new drug being developed for the treatment of various cancers.
Mar 01, 2007
Pharmaceutical Technology
By Pharmaceutical Technology Editors
Implementing process analytical technology principles can be a challenging task. This article presents a straightforward approach.
Feb 02, 2007
Pharmaceutical Technology
By Pharmaceutical Technology Editors
For solid oral-dosage forms, water testing usually is performed to control the chemical, physical, or microbiological properties of the drug product. Measurements of total water as made with Karl Fischer (KF) techniques is not needed and water-activity often will provide a better correlation with changes in chemical, physical, or microbiological properties than KF techniques. In these cases, water activity testing can easily replace KF testing. Water-activity measurements are nondestructive, require little labor, and the equipment required is generally inexpensive. Only a few simple checks are needed to ensure the validity of measurements. Strategies for implementing water activity testing are described.
Feb 02, 2007
Pharmaceutical Technology
By Pharmaceutical Technology Editors
The objectives of this study were to prepare and characterize inclusion complexes of lovastatin with hydroxypropyl-β-cyclodextrin (HPβ-CD) and to study the effect of the complexes on the dissolution rate of lovastatin (LVS). The findings suggest that LVS's poor dissolution profile can be overcome by preparing its inclusion complex with HPβ-CD.
Feb 02, 2007
Pharmaceutical Technology
By Pharmaceutical Technology Editors
The role of micro-biological testing in real-time release is too important to ignore.
Feb 02, 2007
Pharmaceutical Technology
By Pharmaceutical Technology Editors
As technology for impurity analysis improves, scientists are gaining better information and asking for more regulatory guidance.
Feb 01, 2007
Pharmaceutical Technology Europe
Terpenes are widely used in topical preparations. This paper focuses on the skin penetration of terpenes depending on their physicochemical properties and influence of the type of dermatological vehicle that was used. The structure of human skin and the skin penetration process is also briefly described.
Feb 01, 2007
Pharmaceutical Technology Europe
Raman spectroscopy has become a commonly used technique for physicochemical analysis that possesses many advantages over other analytical techniques. It is a very attractive characterization tool, not least because it enables measurements in water. However, very few examples of its application in an aqueous environment exist in literature. This paper provides some recent applications of Raman spectroscopy in pharmaceutical material and process characterization when water is present.
Jan 01, 2007
Pharmaceutical Technology Europe
In recent years, AI has become important in a number of fields in helping to make better use of information, increasing efficiency and enhancing productivity.
Jan 01, 2007
Pharmaceutical Technology Europe
Nanoparticulate drug carriers include a class of particles made of polymers or lipids that — because of their size and chemical composition —permit systemic and local treatment.
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