Peer-Review Research

Jun 02, 2012
Pharmaceutical Technology
By Pharmaceutical Technology Editors
The authors evaluate the thermal properties of gentamicin sulfate as a small-molecule drug model in optimizing the freeze-drying cycle.
Apr 02, 2012
Pharmaceutical Technology
By Pharmaceutical Technology Editors
In Part III of a three-part article, the authors examine various degradation routes of APIs, impurities arising from interactions in formulations, metabolite impurities, various analytical methods to measure impuritie, and ways to control impurities.
Mar 02, 2012
Pharmaceutical Technology
By Pharmaceutical Technology Editors
In Part II of a three-part article, the authors examine impurities from chiral molecules, polymorphic contaminants, and genotoxic impurities.
Feb 02, 2012
Pharmaceutical Technology
By Pharmaceutical Technology Editors
In Part I of a three-part article, the authors discuss what constitutes an impurity and the potential sources of impurities in APIs and finished drug products.
Jan 02, 2012
Pharmaceutical Technology
By Pharmaceutical Technology Editors
The authors designed an upper punch with a removable punch tip to determine a tablet formulation's propensity to stick by weighing the mass of powder adhered to the punch tip.
Dec 02, 2011
Pharmaceutical Technology
By Pharmaceutical Technology Editors
The authors developed a metronidazole-based floating drug-delivery system to investigate the effect of rate-controlling polymers on release pattern and duration of buoyancy in matrix tablets.
Nov 02, 2011
Pharmaceutical Technology
The authors describe the operational qualification of test accuracy with regard to temperature drift using a thermal-compensation algorithm on several freeze dryers.
Nov 02, 2011
Pharmaceutical Technology
The study evaluates near-infrared analysis of tablets nominally containing 4 mg of chlorpheniramine maleate and 10 mg of phenylephrine hydrochloride per dose.
Oct 02, 2011
Pharmaceutical Technology
By Pharmaceutical Technology Editors
The authors describe the concept of the limiting discriminatory the limiting discriminatory threshold (LDT) as an objective means of evaluating the inherent quality requirement of a large-sample content-uniformity test.
Oct 02, 2011
Pharmaceutical Technology
The authors experiment with a resonant acoustic mixer as a method for dry powder coating.
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