Best Practices

Apr 04, 2016
Non-destructive container closure integrity testing allows 100% inspection of all ampoules, syringes, vials, and cartridges.
Apr 04, 2016
PTSM: Pharmaceutical Technology Sourcing and Management
Texture analyzers can be used to evaluate wall hardness and elasticity of softgel capsules.
Mar 17, 2016
Advanced electronic batch recording (EBR) manages workflows and recordkeeping for compliance and production efficiency.
Mar 14, 2016
Wear-resistant materials and coatings protect tablet punches and dies from abrasive formulations.
Mar 04, 2016
Dedusting equipment and techniques address problems associated with tablet manufacturing dust accumulation.
Feb 26, 2016
Preventive maintenance (PM) is something that pharmaceutical manufacturers should employ on a regular basis, though it remains somewhat alarming to see how many wait until they experience an “uh-oh” moment before acting. Tablet-press manufacturers can offer varying guideposts for the timing of such PM intervals, but there are some easy signals to remain cognizant of that should prompt proactive behavior. A few of these include odd noises, erratic tablet weights, and premature wear on contact parts such as cams and compression rolls. Today’s presses can produce tablets at an astounding rate, with extraordinary accuracy, but only when they are looked after in meticulous fashion. In this article, Matt Bundenthal of Fette Compacting America describes components of a PM program.
Feb 18, 2016
Equipment and Processing Report
Regular removal of residues from disinfectants and sporicidals is important for improved aesthetics and safety in cleanrooms.
Feb 18, 2016
Manufacturing of antibody drug conjugates requires high-containment solutions, such as high-performance aseptic isolators.
Feb 08, 2016
Single-use systems (SUS), also called disposable technology, can improve manufacturing efficiency by reducing the time needed for cleaning and cleaning validations. When implementing disposable technology for aseptic processing, considerations include material compatibility, material sourcing, facility layout, and training. It is important, however, to understand the challenges associated with using SUS and to have plans in place to mitigate risk. Steve Nole and Amanda Hawkins, from CMO Grand River Aseptic Manufacturing (GRAM), spoke with Pharmaceutical Technology about some of the best practices the company has implemented in using SUS.
Nov 24, 2015
Equipment and Processing Report
Pharmaceutical manufacturing facilities can help prevent contamination and cross contamination by using color coding.
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