GMPs/Validation Whitepapers - BioPharm International

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GMPs/Validation Whitepapers

Novel pH Gradient Separation Platform for Monoclonal Antibody Charge Variant Analysis

July 30, 2013

A novel pH gradient method for cation-exchange chromatography is discussed. Linear pH gradient was achieved using a multi-component buffer system containing multiple zwitterionic buffer species with pI values from 6 to 10.

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