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A 25-Year Retrospective on Bio-Engineering

July 1, 2012

Steven S. Kuwahara, PhD, principal consultant at GXP BioTechnology LLC, gives an update on "Engineering the Cell-System Interface."

A New Era in Cell Culture Media Development

July 1, 2012

Cell-line specific complex media supplements combine chemically defined media additives into a single supplement.

Optimizing Expression Systems

July 1, 2012

Industry experts discuss methods for optimizing protein expression in bacterial and mammalian cell lines.

Scale up of Fed-Batch Culture to Produce Plasmid DNA in Escherichia coli (Peer Reviewed)

July 1, 2012

The authors present scale-up from a 5-L fermentor to a 50-L pilot-scale using the criterion of constant power consumption per unit liquid volume.

Allogeneic Versus Autologous Stem-Cell Therapy

July 1, 2012

The author discusses potential manufacturing costs & challenges of allogeneic & autologous stem-cell therapy.

Determining Process Quality Metrics for CMOs

June 1, 2012

Implementing quality by design makes the determination of quality metrics across CMOs and sponsors essential.

Developing Alternatives to ELISA-Based Biomarker Assays

June 1, 2012

The authors discuss a new, rapid immunoassay for the detection of biomarkers.

25 Years of Biopharmaceutical Innovation: An Expert Roundtable

June 1, 2012

Industry experts discuss significant achievements. Plus: What's in store for the future.

25 Years of BioPharma Industry Growth

June 1, 2012

A review of key industry shifts and promises for the future.

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