Articles on disposables: implementation, validation, cost-benefit analysis - BioPharm International


The advantages and disadvantages of disposables, along with cost-benefit analyses, validation strategies, and implementation approaches.

Best Practices in Adopting Single-Use Systems

January 1, 2014

Key considerations for implementing single-use components or platforms when moving from research to process development.

Disposable Applications in Demand by Biopharma

November 1, 2013

Data from BioPlan Associates' 10th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production suggest that the interest in disposable devices has begun to extend to biopharma operations beyond basic single-use bags and connectors.

Protein Purification Using Single-Use Technology

August 2, 2013

Uwe Gottschalk, vice-president of purification technologies, Sartorius Stedim Biotech, discusses specific challenges in protein purification.

A Generic Growth Test Method for Improving Quality Control of Disposables in Industrial Cell Culture

June 1, 2013

Quality control for disposable-bags

Growth in Single-Use Technology Video

May 30, 2013

Rita Peters, Editorial Director for Pharmaceutical Technology and BioPharm Inernational talks with Mani Krishnan, director of systems at EMD Millipore live at Interphex 2013 about single-use technology. In this interview they discuss areas of growth in single-use technology as well as reservations that some companies have to switching to single-use systems Krishnan identifies a few technology advances that are overcoming these objections as well as decision-making strategies for facilities considering a switch to a single-use system.

When the Process Becomes the Product: Single-Use Technology and the Next Biomanufacturing Paradigm

April 2, 2013

The move to single-use manufacturing has prompted a paradigm shift in facility design.

Securing and Qualifying Single-Use Technologies

April 2, 2013

The authors suggest techniques for mitigating risk and securing the supply chain for single-use components used in biopharmaceutical manufacturing.

The Overlooked Benefits of Single-Use Technology: Improved Quality and Increased Patient Safety

April 2, 2013

Reduced carryover risk and close attention to particulate control result in greater patient safety through the use of single-use systems.

Scalability of the Mobius CellReady Single-use Bioreactor Systems

April 2, 2013

Review the process-design space and scalability of a single-use, stirred-tank bioreactor.



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