Articles on disposables: implementation, validation, cost-benefit analysis - BioPharm International


The advantages and disadvantages of disposables, along with cost-benefit analyses, validation strategies, and implementation approaches.

Achieving Supply Chain Excellence in Single-Use Systems

March 1, 2014

For single-use systems, supply chain excellence requires a commitment to problem solving across organization boundaries.

Configuring Manufacturing Operation Management Applications

March 1, 2014

Adopting single-use systems has implications for manufacturing execution systems (MES), process data-analytics tools, and scheduling. Enterprise resource planning and MES must be integrated using standards such as ISA-95. Master and electronic batch records must be designed to capture the details of single-use component assembly to enable traceability.

Cytotoxicity Risks in Single-use Media and Bioreactor Containers

February 1, 2014

Studies show diminished cell growth properties associated with some biocontainer or bioreactor films.

2014 Manufacturing Trends and Outlook

January 1, 2014

Single-use systems and other technologies drive process efficiencies, but there is room for improvement.

Best Practices in Adopting Single-Use Systems

January 1, 2014

Key considerations for implementing single-use components or platforms when moving from research to process development.

Disposable Applications in Demand by Biopharma

November 1, 2013

Data from BioPlan Associates' 10th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production suggest that the interest in disposable devices has begun to extend to biopharma operations beyond basic single-use bags and connectors.

Protein Purification Using Single-Use Technology

August 2, 2013

Uwe Gottschalk, vice-president of purification technologies, Sartorius Stedim Biotech, discusses specific challenges in protein purification.

A Generic Growth Test Method for Improving Quality Control of Disposables in Industrial Cell Culture

June 1, 2013

Quality control for disposable-bags

Growth in Single-Use Technology Video

May 30, 2013

Rita Peters, Editorial Director for Pharmaceutical Technology and BioPharm Inernational talks with Mani Krishnan, director of systems at EMD Millipore live at Interphex 2013 about single-use technology. In this interview they discuss areas of growth in single-use technology as well as reservations that some companies have to switching to single-use systems Krishnan identifies a few technology advances that are overcoming these objections as well as decision-making strategies for facilities considering a switch to a single-use system.



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