Articles on chromatography, filtration, scale-up for proteins, MAbs, vaccines - BioPharm International

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Downstream Processing
The separation and purification steps of biotech processing, including chromatography and filtration. Vaccine and monoclonal antibody (MAb) manufacturing are also found here.

Approaches for Flexible Manufacturing Facilities in Vaccine Production

November 2, 2011

With careful analysis to mitigate risk, disposable technology and process closure can enable adaptable designs and reduced costs.

DNA Vaccine Delivery

October 2, 2011

Development of the ideal DNA vaccine requires the optimization of delivery strategies and plasmid vectors.

Challenges and Trends in Vaccine Manufacturing

October 2, 2011

An evaluation of the technologies needed to develop a safe, effective, and economically efficient vaccine. This article is part of a special section on vaccines.

Contract Services Spending: Who's Spending What, and Where?

October 1, 2011

A survey provides insight into drug companies' plans for spending on outsourced services. This article contains bonus online material.

Technologies for Downstream Processing

September 1, 2011

The author describes recent developments to help overcome the downstream-processing bottleneck.

The Future of Downstream Processing

September 1, 2011

The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies.

Organizational Structures of Process Development and Manufacturing Support

September 1, 2011

How to strike a balance between site autonomy and global coordination.

Analysis of PEGylated Protein by Tetra Detection Size Exclusion Chromatography

August 2, 2011

Reliably detecting low amounts of high molecular weight impurities during process development and characterization of biopharmaceutical products.

Top 1000 Global Biomanufacturing Facilities

August 1, 2011

Insights from real-time ranking of global biomanufacturing capabilities.

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