Articles on chromatography, filtration, scale-up for proteins, MAbs, vaccines - BioPharm International

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Downstream Processing
The separation and purification steps of biotech processing, including chromatography and filtration. Vaccine and monoclonal antibody (MAb) manufacturing are also found here.

Efficient Prion Removal from Gonadotropin Solutions by Nanofiltration Membranes

December 1, 2011

Can a nanofiltration process be leveraged for removal of prions?

The Employment Outlook Brightens

December 1, 2011

Readers react to the economic turmoil of the past year and look longingly forward to 2012.

Approaches for Flexible Manufacturing Facilities in Vaccine Production

November 2, 2011

With careful analysis to mitigate risk, disposable technology and process closure can enable adaptable designs and reduced costs.

Challenges and Trends in Vaccine Manufacturing

October 2, 2011

An evaluation of the technologies needed to develop a safe, effective, and economically efficient vaccine. This article is part of a special section on vaccines.

DNA Vaccine Delivery

October 2, 2011

Development of the ideal DNA vaccine requires the optimization of delivery strategies and plasmid vectors.

Contract Services Spending: Who's Spending What, and Where?

October 1, 2011

A survey provides insight into drug companies' plans for spending on outsourced services. This article contains bonus online material.

Organizational Structures of Process Development and Manufacturing Support

September 1, 2011

How to strike a balance between site autonomy and global coordination.

Technologies for Downstream Processing

September 1, 2011

The author describes recent developments to help overcome the downstream-processing bottleneck.

The Future of Downstream Processing

September 1, 2011

The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies.

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