Articles on chromatography, filtration, scale-up for proteins, MAbs, vaccines - BioPharm International

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Downstream Processing
The separation and purification steps of biotech processing, including chromatography and filtration. Vaccine and monoclonal antibody (MAb) manufacturing are also found here.

An Overview of Risk Assessment Strategies for Extractables and Leachables

January 1, 2012

Approaches for risk assessment of extractables and leachables.

Therapeutic Vaccine Outlook

January 1, 2012

Has an approval in oncology reignited interest in the recruitment of the immune system in the fight against disease?

Ice Fog as a Means to Induce Uniform Ice Nucleation During Lyophilization (Peer Reviewed)

January 1, 2012

The authors describe a novel means to control ice nucleation using a sterile cryogenic ice fog.

The Employment Outlook Brightens

December 1, 2011

Readers react to the economic turmoil of the past year and look longingly forward to 2012.

Efficient Prion Removal from Gonadotropin Solutions by Nanofiltration Membranes

December 1, 2011

Can a nanofiltration process be leveraged for removal of prions?

Approaches for Flexible Manufacturing Facilities in Vaccine Production

November 2, 2011

With careful analysis to mitigate risk, disposable technology and process closure can enable adaptable designs and reduced costs.

DNA Vaccine Delivery

October 2, 2011

Development of the ideal DNA vaccine requires the optimization of delivery strategies and plasmid vectors.

Challenges and Trends in Vaccine Manufacturing

October 2, 2011

An evaluation of the technologies needed to develop a safe, effective, and economically efficient vaccine. This article is part of a special section on vaccines.

Contract Services Spending: Who's Spending What, and Where?

October 1, 2011

A survey provides insight into drug companies' plans for spending on outsourced services. This article contains bonus online material.

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