Articles by Bio-Rad - BioPharm International

ADVERTISEMENT

ADVERTISEMENT

Articles by Bio-Rad

Bio-Rad


http://www.bio-rad.com/

Articles
Separation of Impurities in a Single Step using a Mixed-Mode Chromatography Media
December 27, 2013

MPC™ media is a versatile mixed-mode chromatography media with unique separation properties for multiple polishing applications at process scale. Combined properties of hydroxyapatite and fluoroapatite provides superior clearance performance.

Separation of Impurities in a Single Step using a Mixed-Mode Chromatography Media
October 29, 2013

MPC™ media is a versatile mixed-mode chromatography media with unique separation properties for multiple polishing applications at process scale. Combined properties of hydroxyapatite and fluoroapatite provides superior clearance performance.

Improving Aggregate Removal from Monoclonal Antibody Feed Using High Resolution Cation Exchange Chromatography
August 27, 2013

Nuvia™ HR-S media is a new cation exchanger designed for high resolution of closely related product impurities such as aggregates. It delivers excellent resolution with a final aggregate content of < 0.3% and a high recovery of > 80% from a heterogeneous feed of monoclonal antibody aggregates and monomer. Aggregate content and recovery in the eluate were shown to be a function of the target conductivity measured at the end of collection

Purification of Recombinant Proteins: A Simple Approach to Method Development
June 25, 2013

Using a simple DOE exercise, the authors demonstrate how to elucidate the nature and degree of interaction between various proteins and the binding ligand for Nuvia™ cPrime™ Hydrophobic Cation Exchange Media, thus allowing method developers to quickly and effectively optimize selectivity and define design space parameters.

Sanitization of a Process Chromatography Column
September 1, 2012

Process Chromatography columns must provide a very high level of cleanability to meet the requirements of various regulatory agencies. This study details the sanitary design and cleaning procedure of the Bio-Rad InPlace column.

ADVERTISEMENT

ADVERTISEMENT

Click here