Articles by Bio-Rad - BioPharm International

ADVERTISEMENT

ADVERTISEMENT

Articles by Bio-Rad

Bio-Rad


http://www.bio-rad.com/

Articles
Improving Aggregate Removal from Monoclonal Antibody Feed Using High Resolution Cation Exchange Chromatography
May 26, 2014

Nuvia™ HR-S media is a new cation exchanger designed for high resolution of closely related product impurities such as aggregates. It delivers excellent resolution with a final aggregate content of <0.3% and a high recovery of >80% from a heterogeneous feed of monoclonal antibody aggregates and monomer. Aggregate content and recovery in the eluate were shown to be a function of the target conductivity measured at the end of collection.

Separation of Impurities in a Single Step using a Mixed-Mode Chromatography Media
December 27, 2013

MPC™ media is a versatile mixed-mode chromatography media with unique separation properties for multiple polishing applications at process scale. Combined properties of hydroxyapatite and fluoroapatite provides superior clearance performance.

Separation of Impurities in a Single Step using a Mixed-Mode Chromatography Media
October 29, 2013

MPC™ media is a versatile mixed-mode chromatography media with unique separation properties for multiple polishing applications at process scale. Combined properties of hydroxyapatite and fluoroapatite provides superior clearance performance.

Sanitization of a Process Chromatography Column
September 1, 2012

Process Chromatography columns must provide a very high level of cleanability to meet the requirements of various regulatory agencies. This study details the sanitary design and cleaning procedure of the Bio-Rad InPlace column.

ADVERTISEMENT

ADVERTISEMENT

Click here