Nathalie Frau, PhD, is a senior scientist in purification process development, biotechnology division, Sartorius Stedim North America.
A new downstream purification platform using a salt-tolerant membrane adsorber.
The authors describe the development of an ultra scale-down anion exchange membrane adsorber, and demonstrate scalability to larger-scale devices.
An analysis of flow rate, load density, viral clearance, and cost.
This alternative to column chromatography is suitable for flow-through as well as bind-and-elute purification operations.
Choosing the right tools to enhance the process.
In recent years, disposable membrane chromatography has gained acceptance as a robust device for large-scale processing.