Articles by Angelica Olcott - BioPharm International

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Articles by Angelica Olcott

Angelica Olcott


Articles
Simple and Sensitive Sub-visible Particle Classification for Biopharmaceuticals with Micro-Flow Imaging
June 24, 2014

Micro-Flow Imaging (MFI) provides accurate and sensitive detection of sub-visible particles and protein aggregates in biopharmaceuticals. Even better, MFI can classify particle populations. This application note takes you through how easy it is to develop custom particle filters to get more accurate and sensitive discrimination between the particles in your protein formulations.

Confirming Accurate Particle Counting and Sizing on MFI Systems
February 25, 2014

Micro-Flow Imaging (MFI) provides accurate and sensitive detection of sub-visible particles and protein aggregates in biopharmaceuticals. Confirmation of instrument performance is demonstrated using NIST-traceable polystyrene beads. This application note provides a guide to best practices for handling standards and samples to ensure sensitive, accurate, and repeatable results.

MFI for Particle Characterization of Biopharmaceuticals Today
November 26, 2013

Micro-flow imaging (MFI) is a sensitive, simple and automated method for the routine analysis of sub-visible particles and translucent protein aggregates. This technology provides particle size, count and morphology. Morphology provides the ability to discriminate a wide variety of particle types allowing you to monitor the change in both protein aggregates and other particles over time. This article reviews the application of MFI for monitoring protein aggregates and sub-visible particles in biopharmaceuticals.

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