Capsule Filling Equipment for Small Batches, Highly Potent Drugs

Bosch Packaging Technology’s GKF 720 capsule filling machine for small batches of hard capsules uses a fully automated, washable containment process.
Jul 03, 2018
By Pharmaceutical Technology Editors

Bosch GKF 720Image courtesy of BoschBosch Packaging Technology’s high-precision capsule filling machine, the GKF 720, is designed for small batches of hard capsules. A specially designed platform provides a fully automated, washable containment process for manufacturing highly potent solid pharmaceuticals. The system has occupational exposure band 5 protection, minimal water requirements, 100% defective capsule detection, and a compact design.

In the first cleaning stage of the GKF 720, the components that come into contact with the product are automatically cleaned from above with 200 mL of water, binding the highly potent residual dust. In the second stage, the processing area is manually flushed with a maximum of 10 L of water, completely ridding it of any product residue. The specially designed tabletop and the new dosing stations make sure that no water penetrates the machine room during cleaning. 

The GKF 720 is designed for processing powders, pellets, and tablets. For pellets and micro-dosed powders in particular, it features a patented, automatic height-adjusting pellet station and a manually height-adjustable dosing disk. Together with the Net Weight Detection System and the integrated gravimetric checkweigher, these features allow consistent in-process control (IPC). The regular adjustment of dosed amounts via IPC ensures a stable, capacitive measuring process throughout the production cycle.

The GKF 720 is equipped with a flexible plug-and-play station, which supports rapid changeover, for instance from pellets to powders. The system can be converted in less than five minutes. 

Source: Bosch Packaging Technology 

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