Jeffrey S. Barrett, PhD, is a Research Professor in the University of Pennsylvania School of Medicine and Director of the Laboratory for Applied PK/PD at the Children's Hospital of Philadelphia (CHOP). His research is focused on developing mathematical models to guide the design and analysis of both translational science experiments and clinical trials. These studies are pivotal to the development of new medicines and to improve our understanding of disease biology. Dr Barrett's group develops decision support tools that interface such models with hospital-based medical records systems to guide drug therapy in critically-ill children. Much of his effort has been focused in children with cancer where Dr Barrett works with colleagues at CHOP to a find cure for infant leukemia.
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