Manufacturing

Aug 02, 2004
Pharmaceutical Technology
The results of forced degradation studies indicate the need for alternatives to valerophenone as an internal standard calibration for quantifying ibuprofen in bulk drug and tablet assay samples.
Aug 02, 2004
By Pharmaceutical Technology Editors
Pharmaceutical science and technology innovations
Aug 02, 2004
Pharmaceutical Technology
By Pharmaceutical Technology Editors
Pharmaceutical Science & Technology News
Aug 02, 2004
Pharmaceutical Technology
By Pharmaceutical Technology Editors
The use of stable isotopic analyses to characterize drug products before they leave the manufacturer is explored as a means to identify counterfeit products.
Aug 01, 2004
Pharmaceutical Technology
The electronic tongue technology provides a technically suitable and cost-effective method for screening and directing taste formulation, while eliminating both safety concerns and subjective bias.
Aug 01, 2004
Pharmaceutical Technology
Automated actuation of nasal sprays removes operator bias during measurement of particle size, spray-plume geometry, and delivered dose.
Aug 01, 2004
Pharmaceutical Technology Europe
If an inspection reveals any shortcomings ... a manufacturer may be warned, fined, or its facility closed down until full control can be demonstrated to the satisfaction of the authorities ....
Aug 01, 2004
Pharmaceutical Technology Europe
Tosoh has developed a new product — Toyopearl Toyoscreen that allows fast identification of the optimal resin for your sample. You can develop the optimal conditions for the separation in addition to the determination of the dynamic binding capacity. All the resins prepacked in these columns are real process resins concerning particle size. Results on the small columns can be scaled up to production.
Aug 01, 2004
Pharmaceutical Technology Europe
Resolving the asset headache - the author explains how effective asset management can enable pharmaceutical companies to boost operational profit, increase production uptime and adhere to regulatory standards.
Aug 01, 2004
Pharmaceutical Technology Europe
Rapid structural elucidation of compounds in complex mixtures is a powerful technique in metabolite, degradation and process control applications. The ability to follow the fragmentation pathway through sequential MSn transitions provides added confirmation and increases the selectivity for monitoring compounds of interest in a complex mixture. Previously, the limiting factors in applying this technique were sensitivity at MS4 and higher transitions, and the cycle time required to acquire multiple MSn spectra across a narrow LC peak. Recent developments in trapping, detection efficiencies and scan rates have reduced these limitations and enabled rapid characterization of multiple compounds from single chromatographic runs.
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