EMD Serono and Mersana to Develop Next-Generation Antibody-Drug Conjugates

Jul 01, 2014
By PharmTech Editors

EMD Serono, a subsidiary of Merck KGaA, and Mersana Therapeutics entered an agreement to collaboratively develop next-generation antibody-drug conjugates (ADCs). Mersana and EMD Serono will leverage Mersana's Fleximer technology to generate ADCs for multiple undisclosed targets.

"This new collaboration provides an exciting opportunity to expand our oncology drug discovery and development portfolio into the evolving ADC space," said Dr. Andree Blaukat, head of the Translational Innovation Platform Oncology at EMD Serono, in a press release.

Under the agreement, EMD Serono will provide monoclonal antibodies to Mersana, which will generate the Fleximer-ADCs and conduct drug discovery and preclinical development activities. EMD Serono will be responsible for clinical development and commercialization of any products under an exclusive license from Mersana. In addition to an upfront payment, Mersana is eligible to receive milestones plus royalties on worldwide net sales of products. Further financial details are not being disclosed.

Sources: EMD Serono