Pharmaceutical Excipients For Hot-Melt Extrusion

May 01, 2011
By PharmTech Editors

By Matthias Karl, Dejan Djuric and Karl Kolter

Various physicochemical characteristics of pure polymers and polymer-plasticiser combinations affect the hot-melt extrusion process. The authors examine the influence of glass-transition temperature, melt viscosity, degradation temperature and process settings on the process and its resulting extrudates.

This article was also published in our US sister publication Pharmaceutical Technology and can be read here.