Agreements and pacts - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

Agreements and pacts
The latest pacts from the pharmaceutical supply chain

PTSM: Pharmaceutical Technology Sourcing and Management
Volume 3, Issue 9

The latest pacts from the pharmaceutical supply chain.

Scottsdale, AZ (Aug. 20)AstraZeneca (London) selected Axway's "Synchrony" supply-chain integrity suite to enable track-and-trace as part of product safety data management (PSDM) initiative. AstraZeneca's PSDM initiative implements a global infrastructure and strategy across multiple packaging lines and production sites. The initial scope of PSDM includes 25 packaging lines and 12 worldwide sites, not including the US sites or supply chain.

Deerfield, IL and London (Aug. 16)Baxter International announced that its subsidiary in the United Kingdom entered into an advanced supply agreement with the UK Department of Health that contains an option to purchase pandemic influenza vaccine in the event that the World Health Organization declares a pandemic. Baxter will manufacture its pandemic vaccine in a serum-free, vero cell-based system at a cell-culture vaccine facility.

Winnipeg, MB, Canada (Aug. 16)Cangene reported that its contract with the US Centers for Disease Control and Prevention for the supply of vaccinia immune globulin intravenous (human) (VIG) was extended for five more years. The original five-year contract was signed in August 2002. Under that contract, Cangene developed and delivered VIG product to the US Strategic National Stockpile.

London (Aug. 20)Chi-Med's Hutchison MediPharma R&D Limited (Hutchison MediPharma) entered into a drug-discovery and development agreement with Eli Lilly and Company (Indianapolis, IN). Lilly and Hutchison MediPharma will initially collaborate on the discovery and development of pharmaceutical agents focused on targets in oncology and inflammation. Hutchison MediPharma will assume primary responsibility for the discovery phase activities necessary for the identification and selection of several clinical candidates, and Lilly will be responsible for ongoing technical advice and the subsequent Investigational New Drug filing and clinical development of these candidates

Billerica, MA (Aug. 15)Millipore expanded its agreement with Novo Nordisk to provide the biopharmaceutical market with recombinant human insulin, a key cell-culture supplement used to manufacture biologic drugs. Under the terms of the agreement, Millipore will have exclusive worldwide rights to market and sell Novo Nordisk's recombinant human insulin, branded by Millipore as "Incelligent SG" and "Incelligent AF," for cell-culture media applications.

Research Triangle Park, NC (Aug. 14)— Icagen signed a worldwide collaboration and licensing agreement with Pfizer (New York) for the discovery, development, and commercialization of compounds that modulate three specific sodium ion channels. Pfizer will provide $38 million to Icagen during the first two years of the collaboration, including a license fee of $12 million, as much as $15 million through an equity commitment, and research and development funding. The equity commitment comprises a $5-million initial investment in Icagen common stock on the effective date of the agreement and an equity put option that would permit Icagen to sell as much as $10 million of common stock to Pfizer at fair market value during the first 18 months following the signing of the agreement. In addition, Icagen is eligible to receive $359 million in research, development, regulatory, and commercialization milestones for each product.

The ion channel targets of the collaboration help generate electrical signals in nerve fibers that mediate the initiation, transmission, and sensation of pain. Icagen identified compounds that have demonstrated efficacy in pain models during preclinical studies. Icagen also accumulated intellectual property in this area that includes several promising compounds that target sodium channels.


ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
70%
Breakthrough designations
4%
Protecting the supply chain
17%
Expedited reviews of drug submissions
2%
More stakeholder involvement
7%
View Results
Eric Langerr Outsourcing Outlook Eric LangerRelationship-building at Top of Mind for Clients
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerRisk Reduction Top Driver for Biopharmaceutical Raw Material Development
Jill Wechsler Regulatory Watch Jill Wechsler Changes and Challenges for Generic Drugs
Faiz Kermaini Industry Insider Faiz KermainiNo Signs of a Slowdown in Mergers
From Generics to Supergenerics
CMOs and the Track-and-Trace Race: Are You Engaged Yet?
Ebola Outbreak Raises Ethical Issues
Better Comms Means a Fitter Future for Pharma, Part 2: Realizing the Benefits of Unified Communications
Better Comms Means a Fitter Future for Pharma, Part 1: Challenges and Changes
Source: PTSM: Pharmaceutical Technology Sourcing and Management,
Click here