In the Spotlight - Pharmaceutical Technology

Latest Issue

Latest Issue
PharmTech Europe

In the Spotlight
Editors' Picks of Pharmaceutical Science & Technology Innovations

Pharmaceutical Technology
Volume 34, Issue 1, pp. 28

A successful pharmaceutical manufacturer always reevaluates its processes to see how they might be made more efficient. Automated equipment, which often performs tasks more quickly and accurately than humans do, can help a company improve its operations. This month's products show how automation can assist quality-control and manufacturing processes. Telstar's new system reduces the risk of product contamination during lyophilization. An instrument from RTS life sciences can free scientists' time for more sophisticated tasks. Copley Scientific's cup coater enhances quality-control procedures.

System automates lyophilization

LyoGistics system Telstar
Telstar (Barcelona) has added a unit to its LyoGistics series of automated loading systems that is designed for the commercial-scale production of freeze-dried active ingredients. The freeze-drying system automatically loads product trays into the lyophilizer without sliding them across the surface of the chamber shelves. The system also fills trays with liquid product and removes lyophilized product using a vacuum system after the drying process is complete.

The setup incorporates a containment isolator between the product and the operator that limits operator exposure to less than 1 g/m3 during an eight-hour shift. After freeze-dried product has been unloaded, product trays are stored on two independent Tray Storage Carts connected to each side of the main isolator chamber. The isolator system can be broken down easily into modules for inspection and maintenance, according to the company. The product also includes decontamination and cleaning systems.

Instrument modified to handle larger samples

SolidPrep instrument RTS Life Science
RTS Life Science (Manchester, England) introduced two new adaptors for its RTS SolidPrep instrument for tablet and capsule homogenization. The adapters enable the instrument to work with 80- and 120-mL tubes. It can now handle as much as 100 mL of solvent with existing methods that use standard 50- and 100-mL glassware. Operators can fit the adaptors easily and change them without using tools.

SolidPrep tubes have lids that are leak-proof and easy to seal, thus facilitating tablet homogenization. The polypropylene tube containers and lids are compatible with common analytical solvents and extraction media.

Coater aids particle-size measurement

Automatic cup coater Copley Scientific
Copley Scientific (Nottingham, England) has introduced an automatic cup coater for the Next Generation Impactor (NGI), which measures the aerodynamic size of drug particles for inhalation. The unit is designed to provide reproducible coating and improve particle-size measurement accuracy by reducing particle bounce within the NGI.

The instrument automatically dispenses a sticky cup-coating solution into all eight NGI cups simultaneously. The coater recovers excess coating solution and returns it to the storage reservoir. The coater's fans help evaporate the solvent, thus leaving an even layer of coating material. Operators can adjust the speed of the peristaltic pump and modify the drying time according to the viscosity of the solution. The unit decreases vapor pollution and reduces solvent waste.


blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
| Weekly

FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
View Results
Eric Langerr Outsourcing Outlook Eric LangerTargeting Different Off-Shore Destinations
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerAsymmetric Synthesis Continues to Advance
Jill Wechsler Regulatory Watch Jill Wechsler Data Integrity Key to GMP Compliance
Sean Milmo European Regulatory WatchSean MilmoExtending the Scope of Pharmacovigilance Comes at a Price
From Generics to Supergenerics
CMOs and the Track-and-Trace Race: Are You Engaged Yet?
Ebola Outbreak Raises Ethical Issues
Better Comms Means a Fitter Future for Pharma, Part 2: Realizing the Benefits of Unified Communications
Better Comms Means a Fitter Future for Pharma, Part 1: Challenges and Changes
Source: Pharmaceutical Technology,
Click here