In the Spotlight - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

In the Spotlight
Editors' picks of pharmaceutical science and technology innovations.

Pharmaceutical Technology
Volume 34, Issue 7, pp. 26

Tablets are still the predominant dosage form for pharmaceutical products. The drug industry has long experience manufacturing tablets, but equipment and processes keep evolving as new materials and formulations challenge conventional production methods. This month's products were designed to improve the versatility and efficiency of tablet-manufacturing lines. The S250 Smart tablet press from IMA facilitates turret changeover and cleaning processes. DRIAM's DRIACONTI-T pharma film coater includes a cylindrical drum that enables continuous processing. The AF-200(T) capsule filler from ACG North America accurately fills low doses at high speeds.

Film coater enables continuous operation


DRIACONTI-T pharma film coater, DRIAM Coating, Technology, www.driam.com
The DRIACONTI-T pharma film coater from DRIAM (Eriskirch am Bodensee, Germany) is designed to enable continuous operation. The unit's cylindrical drum is divided into sections, each of which is dedicated to a particular process step. When a process step is complete, flaps in the drum move simultaneously to transfer the groups of tablets to the next drum section for further processing. Unlike traditional film coaters, the DRIACONTI-T pharma device can handle batches of all sizes.

Operators can set up the machine so that tablets enter its loading hopper directly from a tablet press. This configuration eliminates the need for loading, unloading, and intermediate storage. The film coater's segmented drum ensures consistent consumption of energy and coating media. The relatively small size of the drum sections enables gentle product handling. Operators can control the machine through a touch-screen monitor. The unit's spraying system can be removed easily.

Tablet press offers flexibility


The S250 Smart auto-mated tablet press IMA www.ima.it
The S250 Smart automated tablet press from IMA (Bologna) was designed to provide flexibility and ease of operation. Operators can lift the device's upper machine head to facilitate turret removal. Using three tools, personnel can remove the turret quickly, swing it out, and position it on a trolley. By lifting the upper machine head, operators also can reach the inside of the press easily, which helps to shorten cleaning time.

The S250 Smart tablet press has a maximum production speed of 300,000 tablets/h. One available model of the machine meets pharmaceutical standards such as 21 CFR 11. The model regulates tablet weight by taking measurements and providing feedback. The device's electric components are included in the machine housing, thus giving the unit a compact design. Personnel operate the press through a touch screen control. The device's software was designed to be self-explanatory.

Encapsulator combines accuracy and high output


AF-200(T) encapsulator ACG North America www.acg-northamerica.com
ACG's (South Plainfield, NJ) AF-200(T) encapsulator is designed to combine microdosing capabilities and output speeds as high as 200,000 capsules/h. The machine fills doses as low as 15 mg with an accuracy of 2 mg. The unit's dosing disc is customized based on formulation characteristics such as bulk density, net content, and slug-forming ability so that the encapsulator achieves the desired fill weight with high accuracy.

The device's feeding design handles difficult formulations (e.g., loose, dusty, and heat-sensitive powders) and reduces dusting to as little as 1%. The feeding design thus enhances operator safety and reduces mechanical changeover time. The unit's proprietary Zero Relative Motion technology helps minimize dust segregation to 1% or less. In addition to powders, the encapsulator also fills capsules with microtablets and pellets. Users control the AF-200(T) machine with a touch screen and adjust its speed with the main panel. The encapsulator is appropriate for facilities with limited floor space.

New Product Announcements

May be sent to New Products Editor, Pharmaceutical Technology, 485 Route One South, Building F, First Floor, Iselin, NJ 08830, fax 732.596.0005,
.

ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
29%
Breakthrough designations
10%
Protecting the supply chain
43%
Expedited reviews of drug submissions
10%
More stakeholder involvement
10%
View Results
Jim Miller Outsourcing Outlook Jim Miller Health Systems Raise the Bar on Reimbursing New Drugs
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerThe Mainstreaming of Continuous Flow API Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler Industry Seeks Clearer Standards for Track and Trace
Siegfried Schmitt Ask the Expert Siegfried SchmittData Integrity
Sandoz Wins Biosimilar Filing Race
NIH Translational Research Partnership Yields Promising Therapy
Clusters set to benefit from improved funding climate but IP rights are even more critical
Supplier Audit Program Marks Progress
FDA, Drug Companies Struggle with Compassionate Use Requests
Source: Pharmaceutical Technology,
Click here