Editors' Picks of Pharmaceutical Science & Technology Innovations
In our difficult economy, pharmaceutical manufacturers are searching for ways to improve efficiency in their production lines.
The first factor to examine is the equipment itself. Vendors are introducing new machines designed to use less power and to
perform more than one application. At the same time, drugmakers and vendors alike are attentive to the role of equipment in
ensuring high drug quality. This month's products play various roles in the manufacturing process. Fristam's positive-displacement
pump facilitates maintenance. Fitzpatrick's roller compactor incorporates an efficient deaeration system. A top-entering agitator
from Chemineer helps improve reduce the power demands of users' processes.
Pump facilitates cleaning and maintenance
The FKL "A" positive-displacement pumps from Fristam Pumps (Middleton WI) are built according to a split-gearbox design that
helps users replace bearings and gears. The machines also incorporate labyrinth-style bearing isolators in place of lip seals.
The bearing isolators provide a solid barrier that keeps gearbox oil inside and prevents external products and high-pressure
spray from entering into the gearbox oil.
FKL "A" pump Fristam Pumps www.fristam.com
In addition, the pump's exterior edges are rounded so that no water sits on top of the device during cleaning, says Duane
Ehlke, Fristam's director of operations. Users do not need to disassemble the device for cleaning in place (CIP). Instead,
operators can turn the rotors slowly and run CIP solution through the pump to clean it fully. This characteristic reduces
the risk of damaging machine parts and decreases downtime.
Agitator helps optimize processes
Chemineer's (Dayton, OH) Model 20 HT/GT top-entering agitator provides various gear ratios to help optimize users' processes
and mechanical designs. The Model 20 offers more output-speed options than previous units, thus enabling operators to reduce
the power demands for a given process by as much as 25%.
Model 20 HT/GT top-entering agitator Chemineer www.chemineer.com
The agitator's tapered roller output bearing design improves the system's integrity by reducing vibration levels, minimizing
rises in temperature, and enhancing the rigidity of the output shaft, which keeps the gearing in contact. The Model 20 device
also can operate in an up-pumping or down-pumping mixer configuration.
Roller compactor provides efficiency and flexibility
The Fitzpatrick Company (Elmhurst, IL) designed its CCS 1025 contained Chilsonator system to process various products efficiently.
The system's high-speed vertical precompression feed screw provides a uniform downward force on the product, thus helping
to feed it to the nip region of the rolls. The vertical orientation and speed of the screw are intended to ensure that product
is distributed across the face of the rolls evenly. The feed screw's vertical orientation provides a path upward for air that
is aspirated from the process, thus creating an efficient deaeration system.
CCS 1025 Chilsonator system The Fitzpatrick Company www.fitzmill.com
The CCS 1025 system is designed to positively seal the product inside the process areas. Operators can disassemble the device
easily for cleaning and reconfiguration. The system includes a wash-in-place to simplify cleaning. The CCS 1025 machine's
roll and size-reduction housing is designed as an integrated unit to minimize headroom requirements. Users can install the
device in wall or as a free-standing unit.