May 2009 Editor's Picks: Products from Continental Disc and Filimatic - Pharmaceutical Technology

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May 2009 Editor's Picks: Products from Continental Disc and Filimatic


Equipment and Processing Report

Featured products from Pharmaceutical Technology's monthly newsletter, Equipment & Processing Report

product Continental Disc
Rupture disc withstands severe conditions

Continental Disc (Liberty, MO) has added the MP unit to its SanitRX series of rupture discs. The product was designed for applications during which conditions frequently change between positive pressure and vacuum. The company moved the disc’s score line from the contact side to the downstream side so that it is subject to less stress when pressure changes. The new position also improves the disc’s cleanability. The disc can be cleaned or steamed in place.

The disc complies with the American Society for Mechanical Engineers’s bioprocessing equipment criteria for process-side surface finish and fully traceable metal and elastomer materials. The component also is free of polishing compounds, release agents, and animal derivatives. The disc’s flow-resistance values are 1.13 for gas and 1.60 for liquid. The disc is appropriate for pressure-vessel applications such as autoclaves, fermenters, and heat exchangers.

 


productFilamatic
Adaptive filling machine

Filamatic’s (Baltimore, MD) AdaptaFil semiautomatic filling machine now offers interchangeable peristaltic, gear, lobe, and piston pumps. Pump changeover does not require tools and enables users to adapt the device to run new products. Changeover also reduces operators’ need to learn how to use new equipment, says Jack Chopper, chief electrical engineer for Filamatic.

The unit can operate at production scale and can be incorporated into an automatic filling line. The filler’s human–machine interface allows operators to save and retrieve recipes by name and number, copy recipes to other machines, and change fill setups easily. The machine’s software system provides control over fill speeds and delay time between fill segments. Users can calibrate a fill with the push of a button.

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Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
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Reducing drug shortages
32%
Breakthrough designations
8%
Protecting the supply chain
40%
Expedited reviews of drug submissions
8%
More stakeholder involvement
12%
View Results
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Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerThe Mainstreaming of Continuous Flow API Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler Industry Seeks Clearer Standards for Track and Trace
Siegfried Schmitt Ask the Expert Siegfried SchmittData Integrity
Sandoz Wins Biosimilar Filing Race
NIH Translational Research Partnership Yields Promising Therapy
Clusters set to benefit from improved funding climate but IP rights are even more critical
Supplier Audit Program Marks Progress
FDA, Drug Companies Struggle with Compassionate Use Requests
Source: Equipment and Processing Report,
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