Week of Jan. 30, 2012: Amgen Agrees to Micromet for $1.16 Billion; Cephalon Issues Recall of Treanda; and More - Pharmaceutical Technology

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Week of Jan. 30, 2012: Amgen Agrees to Micromet for $1.16 Billion; Cephalon Issues Recall of Treanda; and More

ePT--the Electronic Newsletter of Pharmaceutical Technology

Company Notes

Amgen has agreed to acquire the biotechnology company Micromet for approximately $1.16 billion ($11 per share in cash). The transaction was unanimously approved by both companies’ boards of directors and includes blinatumomab, a bispecific T-cell engager (BiTE) antibody in Phase II clinical development for treating acute lymphoblastic leukemia and non-Hodgkin’s lymphoma, as well as proprietary BiTE antibody technology. Read More

Catalent Pharma Solutions has expanded its controlled-release drug-development and supply capabilities at its Schorndorf, Germany, facility. The expansion includes the addition of R&D and commercial-scale fluid–bed technology, OptiMelt hot-melt extrusion capabilities, and additional cGMP compliance for handling OEB Class III customer products. Read More

Celgene, a biopharmaceutical company, has agreed to acquire the clinical-stage biotechnology company Avila Therapeutics for up to $925 million. The acquisition provides Celgene with Avila’s AVL-292, a highly selective Bruton’s tyrosine kinase (Btk) inhibitor for treating hematologic cancers, currently in Phase I clinical development. In addition, Avila’s proprietary Avilomics platform, which is used to produce covalent drugs that achieve protein silencing. Read More

Kerry Ingredients & Flavors, a provider of functional ingredients, is investing $10 million in expanding its Beloit, Wisconsin, facility to include a cell-science laboratory. The expansion will feature a consumer nutrition center, flavor laboratories, and product ideation and customer collaboration suites. The project is expected to be complete by August 2012, and will add an additional 30,000 ft2 to the existing 260,000-ft2 facility. Read More

Teva Pharmaceutical Industries’s subsidiary Cephalon has issued a voluntary recall of Treanda (bendamustine hydrochloride) for injection (25mg/8mL), lot TB30111), for treating indolent B-cell non-Hodgkin’s lymphoma, after glass fragments were discovered in a single vial. The affected Treanda lot is packaged in 8-mL vials and was distributed to wholesalers and distributors nationwide between Mar. 22, 2011, and Oct. 5, 2011. Read More

Industry Briefs:

A roundup of other company and people news from pharmaceutical and biopharmaceutical companies, their suppliers, and contract-service providers. Read More


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