December 2009 Editor's Picks: Products from Sepha and AdvantaPure - Pharmaceutical Technology

Latest Issue

Latest Issue
PharmTech Europe

December 2009 Editor's Picks: Products from Sepha and AdvantaPure

Equipment and Processing Report

Featured products from Pharmaceutical Technology's monthly newsletter, Equipment & Processing Report

product Sepha
Leak-testing machine reduces waste

Sepha’s (Belfast, Northern Ireland) Blisterscan is a nondestructive, noncontact leak-testing machine for blister packs. The machine scans blister packs with a laser beam before and after applying a vacuum to them. It examines the difference between scans to determine the size of the hole in the blister pack. The instrument detects leaks as small as 7 µm in diameter and locates the exact pocket that leaks.

Because the Blisterscan method is nondestructive, packs that pass the test can be returned to the production line. If a pack fails the test, an operator can empty its contents for repackaging. The Blisterscan unit thus reduces the amount of wasted product. In addition, the unit can be fully validated, unlike the blue-dye test, which requires a subjective operator decision about whether a pack passes or fails. The Blisterscan machine is intended to automate the quality-assurance process and facilitate compliance with current good manufacturing practices standards.

Identification method improves trackability

AdvantaPure (Southampton, PA) has introduced its DocuLink method of distinguishing silicone manifolds after installation. The company assigns each manifold a unique identification number and permanently molds a silicone-encased label with this information within the manifold’s silicone connector. This method can be applied to T, Y, cross, reducer, or molded Tri-Clamp connectors. Operators can use a manifold’s identification number to view its related documents such as certificates of compliance, component specifications, and validations on an online data-management site.

AdvantaPure’s DocuLink labels and silicone manifolds withstand autoclaves, gamma irradiation, clean-in-place, and steam-in-place sterilization processes. The DocuLink labels do not contact the products within the manifolds. The DocuLink method is designed to facilitate manifold trackability and ease users’ safety concerns. Because the unit eases document retrieval, it could reduce the time and expense related to audits and validations.


blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
| Weekly

Which of the following business challenge poses the greatest threat to your company?
Building a sustainable pipeline of products
Attracting a skilled workforce
Obtaining/maintaining adequate financing
Regulatory compliance
Building a sustainable pipeline of products
Attracting a skilled workforce
Obtaining/maintaining adequate financing
Regulatory compliance
View Results
Eric Langer Outsourcing Outlook Eric LangerBiopharma Outsourcing Activities Update
Cynthia Challener, PhD Ingredients Insider Cynthia Challener, PhDAppropriate Process Design Critical for Commercial Manufacture of Highly Potent APIs
Jill Wechsler Regulatory Watch Jill Wechsler FDA and Manufacturers Seek a More Secure Drug Supply Chain
Sean Milmo European Regulatory WatcchSean MilmoQuality by Design?Bridging the Gap between Concept and Implementation
Medicare Payment Data Raises Questions About Drug Costs
FDA Wants You!
A New Strategy to Tackle Antibiotic Resistance
Drug-Diagnostic Development Stymied by Payer Concerns
Obama Administration Halts Attack on Medicare Drug Plans
Source: Equipment and Processing Report,
Click here