July 2012 Editor's Picks: Products from Sartorius Stedim Biotech and Waters - Pharmaceutical Technology

Latest Issue

Latest Issue
PharmTech Europe

July 2012 Editor's Picks: Products from Sartorius Stedim Biotech and Waters

Equipment and Processing Report

Featured products from Pharmaceutical Technology's monthly newsletter, Equipment & Processing Report

Sartorius Stedim Biotech

Sterilizing-grade filter improves biopharmaceutical manufacturing efficiency

Sartorius Stedim Biotech’s (SSB) Sartopore Platinum sterilizing-grade filter for biopharmaceutical manufacturing improves product yields and filtration performance. The surface of the polyethersulfone filter membrane has been modified using a hydrophilic, thermostable polymer. This surface modification increases wetting properties, which reduces the amount of water for injection needed to wet the cartridge, and minimizes protein binding, which increases product yield. The membrane has been pleated using SSB’s newly developed, proprietary TwinPleat process. The alternating long and short pleats of the membrane increase the filter area of a 10 in. cartridge by more than 60%. At the same time, this geometry ensures that liquids flow through the entire filter area so that the filtration capacity of the cartridge is used to the fullest extent, which improves filtration performance and lower filtration costs. The filter cartridges can be dry-steam sterilized in the forward or the reverse direction without altering the properties of their membrane.  The filters can be used in the entire pH range from 1 to 14.

Mass spectrometers with increased sensitivity reduce laboratory downtime

Waters added its StepWave ion optics technology to its new Xevo G2-S QTof and Xevo G2-S Tof benchtop, time-of-flight mass spectrometers (MS), which makes them up to twenty times more sensitive than earlier-generation instruments.  StepWave ion optics technology transfers ions efficiently while actively filtering out undesirable neutral contaminants. As a result, MS signals are increased and, because critical components in the device stay clean for longer periods of time, quantitative results are more reproducible and laboratories experience less downtime due to routine cleaning and maintenance.  The instruments are designed to work with Waters ACQUITY UltraPerformance LC System and are capable of achieving low detection limits with minimal sample volumes.


blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
| Weekly

FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
View Results
Eric Langerr Outsourcing Outlook Eric LangerTargeting Different Off-Shore Destinations
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerAsymmetric Synthesis Continues to Advance
Jill Wechsler Regulatory Watch Jill Wechsler Data Integrity Key to GMP Compliance
Sean Milmo European Regulatory WatchSean MilmoExtending the Scope of Pharmacovigilance Comes at a Price
From Generics to Supergenerics
CMOs and the Track-and-Trace Race: Are You Engaged Yet?
Ebola Outbreak Raises Ethical Issues
Better Comms Means a Fitter Future for Pharma, Part 2: Realizing the Benefits of Unified Communications
Better Comms Means a Fitter Future for Pharma, Part 1: Challenges and Changes
Source: Equipment and Processing Report,
Click here