March 2012 Editor's Picks: Products from EMD Millipore and Powder Systems - Pharmaceutical Technology

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March 2012 Editor's Picks: Products from EMD Millipore and Powder Systems

Equipment and Processing Report

Featured products from Pharmaceutical Technology's monthly newsletter, Equipment & Processing Report

EMD Millipore

EMD Millipore introduces a larger, 1000-L mixing container for single-use powder mixing and delivery.
Single-use powder mixing and delivery system now available in 1000-L size
EMD Millipore, the life-science division of Merck KGaA, added a larger, 1000-L system to its line of Mobius mixers, which already includes 100-, 200-, and 500-L sizes. The systems use integrated, single-use, powder delivery, mixing, and filtration technology, which gives biopharmaceutical manufacturers increased operational flexibility and decreases process and validation time and contamination risk.

“We are seeing an increased number of new applications for single-use technologies. It is now common to see single-use mixing systems and storage systems in pilot and production scale. With the introduction of the Mobius 1000-L single-use mixer, we are providing our customers with a wider range of volumes for increased flexibility to meet their specific processing needs,” say senior applications engineer Sue Walker and product development engineer John Saragosa of EMD Millipore.

The 1000-L single-use mix container ships in an “easy-fold” format for simple unfolding during installation. The stainless-steel mixer carrier features a double jacket for efficient heat exchange at the sides and, new to the 1000-L size, at the bottom as well. The mixer has load cells for weight measurement and a thermowell for temperature measurement.

Powder Systems

The ARTMiS Automated RealTime Milling System within Powder Systems’s containment unit provides an advanced processing solution for jet milling of powders.
Automated milling system provides an advanced processing solution for jet milling of powders

Containment-unit supplier Powder Systems Ltd (PSL) collaborated with the suppliers of the ARTMiS Automated RealTime Milling System to provide a secure, isolated milling suite. The ARTMiS system, introduced last year, combines Sturtevant’s Micronizer Jet Mill, Malvern’s Insitec particle-size analyzer, and Schenck’s AccuRate PureFeed feeder in a fully automated system that simplifies and optimizes the jet-milling process. For high-potency or high-value materials that need containment of the jet-milling process, the PSL isolator provides containment to nanogram levels. The isolator was designed for enhanced operator viewing using an L-shaped window. The glove ports and cabinet-depth were designed ergonomically so that all parts of the isolator can be reached without stretching, says Stuart Evans, product engineer at PSL. An assured explosion protection system is integrated into the design. PSL offers an optional nitrogen purge system that is able to achieve less than 1% relative humidity.

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