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Bentley, Cardinal Health to Scale-Up Clinical Supplies for Intranasal Insulin

September 21, 2006

ePT--the Electronic Newsletter of Pharmaceutical Technology

Specialty Pharmaceutical Company Bentley Pharmaceuticals has entered into an agreement with Cardinal Health for the scale-up of clinical supplies for Bentley's intranasal insulin product candidate.

India's Pharmaceutical Machine Manufacturers: From Imitation to Innovation

April 2, 2007

Pharmaceutical Technology

Indian pharmaceutical machine manufacturers (IPMMs) are exceptional among their foreign counterparts. Historically similar to the Chinese with regard to copycat practices, patent infringements, and substandard quality, the IPMMs have made great strides in innovation and collaboration to break free from the shackles of this paradigm.

Supply Chain Technology, Real-Time Quality System Win Microsoft Awards

June 22, 2006

ePT--the Electronic Newsletter of Pharmaceutical Technology

Microsoft Corporation (Redmond, WA) announced the winners of the Microsoft Pharmaceuticals and Life Sciences Innovation Awards 2006 at this year?s meeting of the Drug Information Association in Philadelphia, Pennsylvania. A four-person panel of industry experts selected winners for the innovative use of Microsoft products in pharmaceutical and life sciences business processes and practices.

Oral Insulin Delivery Strategies Using Absorption Promoters,

April 2, 2006

Pharmaceutical Technology

Absorption promoters and enhancers and enzyme inhibitors, either alone or in combination, can play an important role in improving the bioavailability of oral insulin.

Nanoparticle Formation: A Modular High Pressure System to Enhance Biopharmaceutical Properties of Poorly Soluble Drugs

March 2, 2006

Pharmaceutical Technology

A modified modular high-pressure system can form nanosuspensions of model compounds by individually controlling cavitation, impact, and shear forces.

Nefopam Containing Transdermal-Matrix Patches Based on Pressure-Sensitive Adhesive Polymers

March 2, 2006

Pharmaceutical Technology

Transdermal matrix-type patches of Nefopam hydrochloride with a combination of pressure-sensitive adhesives were developed. The polymeric composition provided a controlled and sustained release of the drug from the patches and demonstrated favorable physicochemical characteristics.

Polymers for Controlled Release Formulation Follows Function
Maribel Rios

June 2, 2005

Pharmaceutical Technology

Once considered mainly an afterthought in a company's lifecycle-management strategy, controlled-release dosage forms are now positioned at the forefront of many formulation strategies. In contrast to drug discovery, formulation work focuses not only on the intricacies of the active pharmaceutical ingredient (API), but also on fine-tuning the excipients, the release profile, and the delivery mechanism to provide optimal therapeutic benefit. Because of their wide range of applications and functionalities, especially in controlled-release therapies, polymers are among the most widely used excipients.

A New Concept in Aseptic Filling: Closed-Vial Technology

May 1, 2005

Pharmaceutical Technology

A ready-to-fill closed vial can improve aseptic filling quality and reduce process complexity.

Isolator Decontamination Using Chlorine Dioxide Gas

April 2, 2005

Pharmaceutical Technology

The authors argue that chlorine dioxide (CD) is a safe and effective decontaminating agent that can be used for challenging applications.The effectiveness of CD gas for sterilizing complex isolator systems is studied.

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Jim Miller Outsourcing Outlook Jim MillerCMO Industry Thins Out
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerFluorination Remains Key Challenge in API Synthesis
Marilyn E. Morris Guest EditorialMarilyn E. MorrisBolstering Graduate Education and Research Programs
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