In the Spotlight - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

In the Spotlight

Pharmaceutical Technology

Robust module facilitates filter changes


RFM22 ducted-terminal filter module (Camfil Farr)
The "RFM22" ducted-terminal filter module from Camfil Farr (Riverdale, NJ) features a design that facilitates filter changes. The unit has retainer clips that hold a filter securely in place and can be adjusted to remove a filter. The RFM22 filter module is the first in the pharmaceutical industry to use such clips to secure a filter, according to Charlie Seyffer, manager of technical materials at Camfil Farr. The module's static pressure port helps users evaluate filter-pressure drop and sample the upstream aerosol concentration during filter-scan testing, thus facilitating filter change and airflow adjustment.

The RFM22 module is constructed of aluminum with welded seams on the room side to ensure structural rigidity and prevent leaks from the contaminated side to the cleanroom side. The unit's hanging tabs are welded to the hood, thus blocking a common leak path.

Rupture disks provide high-volume flow


Sigma Series rupture disk (BS&B Safety Systems)
The "Sigma Series" rupture disks from BS&B Safety Systems (Tulsa, OK) enable high gas and liquid volume flow. The disks achieve operating pressures as high as 95%. The units' ability to withstand these high pressures reduces fatigue, allows the disks to last longer between replacements, and minimizes plant downtime.

The Sigma Series disks incorporate BS&B's "SAF" technology, which allows them to accurately achieve various burst pressures. The technology also provides a damage–safety ratio of ≤1, thus ensuring that an inadvertently damaged disk will rupture at or below its marked burst pressure. The disks' circular score prevents fragmentation when the units do burst.

In addition, the units incorporate a pretorqued "SRB-7RS" safety holder that allows them to be removed and inspected without requiring the values to be retorqued. The rupture disks are available in several sizes, and models are made of corrosion-resistant materials.

Auger feeder avoids cross contamination


PureFeed AP-300 auger feeder (Schenck AccuRate)
The "PureFeed AP-300" auger feeder from Schenck AccuRate (Whitewater, WI) features a recyclable and disposable feed hopper to prevent cross contamination when users change materials. The flexible feed hopper and programmable external dual-arm agitation system enable the device to handle various materials. The disposable feed hopper is designed to reduce cleaning time.

The unit is available in volumetric and gravimetric configurations for applications that require 0.5–150-kg/h feed rates. Extension hoppers and covers are available in 4-, 12-, and 36-L sizes.

The feeder's connections are made using sanitary quick-release clamps. These characteristics facilitate disassembly, cleaning, and maintenance. The unit has 316 L stainless steel parts and 32-microinch RA finishes on all contact surfaces.

ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
33%
Breakthrough designations
11%
Protecting the supply chain
39%
Expedited reviews of drug submissions
11%
More stakeholder involvement
6%
View Results
Jim Miller Outsourcing Outlook Jim Miller Health Systems Raise the Bar on Reimbursing New Drugs
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerThe Mainstreaming of Continuous Flow API Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler Industry Seeks Clearer Standards for Track and Trace
Siegfried Schmitt Ask the Expert Siegfried SchmittData Integrity
Sandoz Wins Biosimilar Filing Race
NIH Translational Research Partnership Yields Promising Therapy
Clusters set to benefit from improved funding climate but IP rights are even more critical
Supplier Audit Program Marks Progress
FDA, Drug Companies Struggle with Compassionate Use Requests
Source: Pharmaceutical Technology,
Click here