Editors' Picks of Pharmaceutical Science & Technology Innovations
THE LATEST IN AUTOMATION/IT/PROCESS CONTROL
Dynamic light scattering system measures microrheology and protein structure
The Zetasizer Nano ZSP is an addition to the Malvern Instruments' range of dynamic light scattering (DLS) systems. The Nano
ZSP measures both size and zeta potential (i.e., electrophoretic mobility) of proteins. A new protein mobility measurement
type in the software that controls data acquisition guides the user through the measurement and assesses and reports on data
quality. The Nano ZSP uses a new version of Zetasizer software that enables microrheology measurements for the first time
on Zetasizer instruments. This DLS-based optical technique allows rheological characterization of weakly-structured and highly
strain-sensitive materials using only microliter-sample volumes.
Systems are available worldwide
Updated process optimization software offers usability enhancements
The latest version of Aspen Technology's aspenONE software (V8) provides new functionality, and usability and visualization
enhancements. For manufacturing and supply chain purposes, the software features adaptive process control, which automates
many tasks and makes maintenance a continuous process. The software also includes the company's Aspen Collaborative Demand
Manager, which provides information to help manage different forecasting requirements. Other features include energy and economic
analysis and solids modeing functionality.
Aspen Technology, Inc.
Software is available worldwide
iPad app for mass spectrometry applications
The Overlap Evaluator iPad app from Hiden Analytical is a reference tool for users of mass spectrometers operating in the
fields of vacuum science and vacuum processing, and for research involving real-time gas-analysis systems. The evaluator enables
the user to create a mass spectral overview of multiple fragmentation spectra to identify the mass peaks with least spectral
interference, and therefore, most suited to species monitoring, and includes a quick mass peak look up table from a library
of common gas and vapor species.
App is available worldwide
Technology offers nucleation process control in freeze drying
SP Scientific's ControLyo Nucleation On-Demand Technology can be retrofitted to range of previously installed production freeze
dryers and can help to make the freezing step more repeatable. The random nature of nucleation has often prevented the freezing
step of lyophilization from being controlled, but SP Scientific's technology helps to regulate the nucleation temperature.
As well as offering greater control over cycle optimization, the technology can also help improve vial-to-vial uniformity,
reduce cycle times, reduce protein aggregation and enable easier process scale-up. In addition, the technology can help lyophilization
processes to adhere to process analytical technology and quality-by-design initiatives.
Contact company for details of availability