Cellectis Enters Agreement With CELLforCURE - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

Cellectis Enters Agreement With CELLforCURE



Cellectis, a company focused on the development of adoptive immunotherapies based on engineered allogeneic Universal Chimeric Antigen Receptor T-cells (UCART) and CELLforCURE, a subsidiary of the biopharmaceutical group LFB, have entered into an agreement in which CELLforCURE will be responsible for the cGMP manufacturing of clinical batches of Cellectis’ allogeneic CART cells. CELLforCURE operates a commercial industrial facility for the production of new therapeutic cell therapies in Les Ulis, France.

The candidates from the UCART product family are allogeneic cell therapy products based on the CAR (Chimeric Antigen Receptor) technology combined with genome engineering. According to the company, engineered allogeneic T-lymphocytes bearing a CAR directed at a tumor antigen are a new potential treatment for the various forms of leukemias, lymphomas, and solid tumors. UCARTs are “off-the-shelf” allogeneic products, which means that UCART production can be standardized, with consistent pharmaceutical release criteria, over time and from batch to batch. The favorable cost of such industrially manufactured treatments may help make them available to a broad patient population and avoid risks associated with the processing and the timing required for an autologous CART process.

Source: Cellectis

ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
27%
Breakthrough designations
9%
Protecting the supply chain
41%
Expedited reviews of drug submissions
9%
More stakeholder involvement
14%
View Results
Jim Miller Outsourcing Outlook Jim Miller Health Systems Raise the Bar on Reimbursing New Drugs
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerThe Mainstreaming of Continuous Flow API Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler Industry Seeks Clearer Standards for Track and Trace
Siegfried Schmitt Ask the Expert Siegfried SchmittData Integrity
Sandoz Wins Biosimilar Filing Race
NIH Translational Research Partnership Yields Promising Therapy
Clusters set to benefit from improved funding climate but IP rights are even more critical
Supplier Audit Program Marks Progress
FDA, Drug Companies Struggle with Compassionate Use Requests

Click here