DSM Signs Supply Pacts with Opthea and Sanquin - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

DSM Signs Supply Pacts with Opthea and Sanquin



Untitled Document

DSM Pharmaceutical has developed supply pacts with Opthea and Sanquin. The agreement with Opthea of Melbourne, Australia covers process development and cGMP manufacture by DSM for Opthea's lead molecule, a soluble form of human VEGFR-3 that blocks the activity of both VEGF-C and VEGF-D, which promote blood and lymphatic vessel formation and are involved in the progression of eye diseases.

This project represents an agreement for process development at DSM Biologics' Groningen, the Netherlands, facility and manufacture at the company’s newly established cGMP facility in Brisbane, Australia. Opthea, a private 100% owned subsidiary of Circadian Technologies is developing its lead molecule OPT-302, previously known as VGX-300, initially for the treatment of "wet" (neovascular) age-related macular degeneration.

In other news, DSM has signed an agreement with the Sanquin Blood Supply Foundation for the commercial manufacture of a monoclonal antibody (mAb) used for the recovery and purification of coagulation factor IX from human blood. Collaboration between DSM Biologics, a business unit of DSM Pharmaceutical Products, and Sanquin will entail subsequent GMP manufacture of the antifactor IX mAb at DSM Biologics’ facilities in Groningen, the Netherlands.

DSM becomes a second supplier to Sanquin for a process intermediate that is used for the capture of human factor IX from blood plasma.

Source: DSM Pharmaceutical

ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
27%
Breakthrough designations
9%
Protecting the supply chain
41%
Expedited reviews of drug submissions
9%
More stakeholder involvement
14%
View Results
Jim Miller Outsourcing Outlook Jim Miller Health Systems Raise the Bar on Reimbursing New Drugs
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerThe Mainstreaming of Continuous Flow API Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler Industry Seeks Clearer Standards for Track and Trace
Siegfried Schmitt Ask the Expert Siegfried SchmittData Integrity
Sandoz Wins Biosimilar Filing Race
NIH Translational Research Partnership Yields Promising Therapy
Clusters set to benefit from improved funding climate but IP rights are even more critical
Supplier Audit Program Marks Progress
FDA, Drug Companies Struggle with Compassionate Use Requests

Click here