Research Project Targets Tablet Sticking - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

Research Project Targets Tablet Sticking



As part of an ongoing collaboration into tabletting science, I Holland and the UK’s University of Nottingham have launched a two-year programme to investigate the cause of tabletting sticking. According to a press release, tablet sticking is one of the biggest problems facing tablet manufacturers today.

The project, titled the Tabletting Science Anti-stick Research (TSAR) project, will use advanced technology, such as scanning electron microscopy, laser profilometry, atomic force microscopy, X-ray photoelectron spectroscopy, Raman spectroscopy, time flight secondary-ion mass spectrometry and adhesion mapping. One particular issue that will be investigated is what makes formulations stick to tablet tooling surfaces, including why certain coatings resist sticking, whereas others do not. Currently, a number of interactions are believed to influence tablet sticking including Van der Waals forces, capillary action, deformation mechanics and static electricity.

The project will be led by Professor Clive Roberts, whose previous research into the quantitative measurements of the surface properties of pharmaceutical materials, using a range of nanoscale techniques, earned him a Queens Award for Industry in 2011.

ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
70%
Breakthrough designations
4%
Protecting the supply chain
17%
Expedited reviews of drug submissions
2%
More stakeholder involvement
7%
View Results
Eric Langerr Outsourcing Outlook Eric LangerTargeting Different Off-Shore Destinations
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerAsymmetric Synthesis Continues to Advance
Jill Wechsler Regulatory Watch Jill Wechsler Data Integrity Key to GMP Compliance
Sean Milmo European Regulatory WatchSean MilmoExtending the Scope of Pharmacovigilance Comes at a Price
From Generics to Supergenerics
CMOs and the Track-and-Trace Race: Are You Engaged Yet?
Ebola Outbreak Raises Ethical Issues
Better Comms Means a Fitter Future for Pharma, Part 2: Realizing the Benefits of Unified Communications
Better Comms Means a Fitter Future for Pharma, Part 1: Challenges and Changes

Click here