Membrane cassettes support high mass transfer - Pharmaceutical Technology

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Membrane cassettes support high mass transfer

Pharmaceutical Technology

Membrane cassettes support high mass transfer


Omega T membrane cassette (Pall Corp.)
Pall Corp. (East Hills, NY) recently unveiled its "Omega T" series membrane cassettes for biopharmaceutical processing applications involving high protein concentrations. The cassettes feature a new, rigid poly-eurethane encapsulate. The polyeureth-ane protects the screen and membrane inside the encapsulate and reduces overtorquing when the cassettes are placed in the holding device. In addition, the polyeurethane has few extractables and therefore yields high-purity solutions.

The Omega T series units also have a new polypropylene screen. The screen's weave and placement within the cassette increase both processing flux rates and product recovery. The screen also supports high mass transfer of proteins and minimizes the gel layer that normally builds up on the membrane. The cassettes' new exterior design incorporates deep notches and rounded edges and fits more snugly in holding devices than Pall's previous units. The cassettes produce scalable results and can purify recombinant proteins or monoclonal antibodies.

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