Protecting the Cold Chain - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

Protecting the Cold Chain
Makers of temperature-sensitive products constantly seek to ensure proper conditions during shipping and storage.


Pharmaceutical Technology


Temperature-sensitive shipments typically include wet ice, dry ice, or gel packs to help maintain refrigerated or frozen conditions inside the container. Wet ice is messy, and dry ice can be dangerous because it can burn exposed skin. All three traditional refrigerant options are relatively heavy and offer no cooling action once thawed. More active cooling is available from a gel-equipped fabric that is conditioned with water and frozen before packing in a process that can be automated for high-volume requirements. An active polymer in the gel holds water in suspension for 6–8 days and stays frozen for 25% longer than an equal mass in a gel pack. Even after thawing, the water sublimes through the fabric and continues to provide evaporative cooling to maintain safe product temperatures for twice as long as traditional refrigerants. The flat, flexible fabric also distributes cold more evenly through the container than wet ice, dry ice, or gel packs ("ThermaFreeze" refrigerant pads, ThermaFreezeProducts Corp., Theo-dore, AL).

Hallie Forcinio is Pharmaceutical Technology's Packaging Forum editor, 4708 Morningside Drive, Cleveland, OH 44109, tel. 216.351.5824, fax 216.351.5684,
.

Company websites

The following is a list of websites for the companies mentioned in this column:
AeroScout, Inc., http://www.aeroscout.com/
Ceebron Pty. Limited, http://www.smart-trace.com/
Cold Chain Technologies, http://www.coldchaintech.com/
Coldkeepers, LLC, http://www.koldtogo.com/
Cryolog, http://www.cryolog.com/
DHL, http://www.dhl.com/
double u products, Inc., http://www.howmanydaysago.com/
Elpro Services Inc., http://www.elpro.com/
Harald H. Temmel KEG, http://www.temmel-austria.com/
Information Mediary Corp., http://www.log-ic.biz/
International Safe Transit Association, http://www.ista.org/
Microlise, http://www.microlise.com/
Minnesota Thermal Science, http:// http://goldenhourtechnology.com/
R.N.C. Industries, Inc., http://www.rncinc.com/
Schreiner MediPharm, http://www.schreiner-medipharm.de/
SecureRF, http://www.securerf.com/
Sensaphone, Inc., http://www.sensaphone.com/
Talecris Biotherapeutics, Inc. http://www.talecris.com/
TCP Reliable, http://www.tcpreliable.com/
Termika US, http://www.termika.us/
ThermaFreezeProducts Corp. http://www.thermafreeze.com/
Timestrip plc, http://www.timestrip.com/


ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
35%
Breakthrough designations
12%
Protecting the supply chain
35%
Expedited reviews of drug submissions
12%
More stakeholder involvement
6%
View Results
Jim Miller Outsourcing Outlook Jim Miller Health Systems Raise the Bar on Reimbursing New Drugs
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerThe Mainstreaming of Continuous Flow API Synthesis
Jill Wechsler Regulatory Watch Jill Wechsler Industry Seeks Clearer Standards for Track and Trace
Siegfried Schmitt Ask the Expert Siegfried SchmittData Integrity
NIH Translational Research Partnership Yields Promising Therapy
Clusters set to benefit from improved funding climate but IP rights are even more critical
Supplier Audit Program Marks Progress
FDA, Drug Companies Struggle with Compassionate Use Requests
USP Faces New Challenges
Source: Pharmaceutical Technology,
Click here