Protecting the Cold Chain - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

Protecting the Cold Chain
Makers of temperature-sensitive products constantly seek to ensure proper conditions during shipping and storage.


Pharmaceutical Technology


Temperature-sensitive shipments typically include wet ice, dry ice, or gel packs to help maintain refrigerated or frozen conditions inside the container. Wet ice is messy, and dry ice can be dangerous because it can burn exposed skin. All three traditional refrigerant options are relatively heavy and offer no cooling action once thawed. More active cooling is available from a gel-equipped fabric that is conditioned with water and frozen before packing in a process that can be automated for high-volume requirements. An active polymer in the gel holds water in suspension for 6–8 days and stays frozen for 25% longer than an equal mass in a gel pack. Even after thawing, the water sublimes through the fabric and continues to provide evaporative cooling to maintain safe product temperatures for twice as long as traditional refrigerants. The flat, flexible fabric also distributes cold more evenly through the container than wet ice, dry ice, or gel packs ("ThermaFreeze" refrigerant pads, ThermaFreezeProducts Corp., Theo-dore, AL).

Hallie Forcinio is Pharmaceutical Technology's Packaging Forum editor, 4708 Morningside Drive, Cleveland, OH 44109, tel. 216.351.5824, fax 216.351.5684,
.

Company websites

The following is a list of websites for the companies mentioned in this column:
AeroScout, Inc., http://www.aeroscout.com/
Ceebron Pty. Limited, http://www.smart-trace.com/
Cold Chain Technologies, http://www.coldchaintech.com/
Coldkeepers, LLC, http://www.koldtogo.com/
Cryolog, http://www.cryolog.com/
DHL, http://www.dhl.com/
double u products, Inc., http://www.howmanydaysago.com/
Elpro Services Inc., http://www.elpro.com/
Harald H. Temmel KEG, http://www.temmel-austria.com/
Information Mediary Corp., http://www.log-ic.biz/
International Safe Transit Association, http://www.ista.org/
Microlise, http://www.microlise.com/
Minnesota Thermal Science, http:// http://goldenhourtechnology.com/
R.N.C. Industries, Inc., http://www.rncinc.com/
Schreiner MediPharm, http://www.schreiner-medipharm.de/
SecureRF, http://www.securerf.com/
Sensaphone, Inc., http://www.sensaphone.com/
Talecris Biotherapeutics, Inc. http://www.talecris.com/
TCP Reliable, http://www.tcpreliable.com/
Termika US, http://www.termika.us/
ThermaFreezeProducts Corp. http://www.thermafreeze.com/
Timestrip plc, http://www.timestrip.com/


ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
FDASIA was signed into law two years ago. Where has the most progress been made in implementation?
Reducing drug shortages
Breakthrough designations
Protecting the supply chain
Expedited reviews of drug submissions
More stakeholder involvement
Reducing drug shortages
70%
Breakthrough designations
4%
Protecting the supply chain
17%
Expedited reviews of drug submissions
2%
More stakeholder involvement
7%
View Results
Eric Langerr Outsourcing Outlook Eric LangerRelationship-building at Top of Mind for Clients
Cynthia Challener, PhD Ingredients Insider Cynthia ChallenerRisk Reduction Top Driver for Biopharmaceutical Raw Material Development
Jill Wechsler Regulatory Watch Jill Wechsler Changes and Challenges for Generic Drugs
Faiz Kermaini Industry Insider Faiz KermainiNo Signs of a Slowdown in Mergers
Ebola Outbreak Raises Ethical Issues
Better Comms Means a Fitter Future for Pharma, Part 2: Realizing the Benefits of Unified Communications
Better Comms Means a Fitter Future for Pharma, Part 1: Challenges and Changes
Sandoz Wins Biosimilar Filing Race
NIH Translational Research Partnership Yields Promising Therapy
Source: Pharmaceutical Technology,
Click here