With SSCI, Aptuit gained solid-form research capabilities, and EaglePicher Pharmaceutical Services gave the company small-molecule
synthesis capabilities, including those for high-potency actives. From InfoPro Solutions Aptuit obtained an informatics suite,
"Clinicopia," for clinical-trials management, information technology staffing, and infrastructure that will serve as the
information spine for Aptuit across all business lines. Pharma Consulting expanded the company's consulting capabilities in
drug development. And the acquisition of Quintiles EDP added capabilities for Aptuit in preclinical technology, pharmaceutical
sciences, and clinical packaging and logistics (CPL). Almedica further added to Aptuit's capabilities and capacity for CPL
and provided a foundation for information technology infrastructure.
Aptuit builds API capabilities
A key move made by Aptuit was the acquisition of EaglePicher Pharmaceutical Services, which provided Aptuit drug-substance
manufacturing capabilities to complement its existing capabilities in dosage-form manufacturing, clinical packaging, and informatics.
With the acquisition of EaglePicher Pharmaceutical Services, Aptuit has a total reactor capacity of 2,500 gallons, which includes
specialized technologies in radiolabeling, high-potency API manufacturing, and cryogenics. Aptuit is investing in the former
EaglePicher facilities in Harrisonville, Missouri. The investment includes upgrades to quality systems and laboratory capabilities,
the addition of dryer capacity, and some additional production capabilities such as hydrogenation. The target completion date
for the larger volume capacity of API manufacturing capability is August–September 2008. Aptuit also is investing in radiolabeling
capability, kilo-scale laboratories, and additional process-development capabilities at its facilities in Kansas City, Missouri.
The radiolabeling and kilo laboratories in Kansas City are scheduled to be on line in December 2007–January 2008.
In all, the company is spending approximately $140 million in internal capital for projects and also plans to invest an additional
$100 million in Aptuit Laurus. The privately held Aptuit has raised as much as $750 million as of April 2006.