Lubrication of Direct-Compressible Blends with Magnesium Stearate Monohydrate and Dihydrate - Pharmaceutical Technology

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Lubrication of Direct-Compressible Blends with Magnesium Stearate Monohydrate and Dihydrate
The influence of magnesium stearate (MgSt) on powder lubrication and finished solid-dose properties presents big challenges to drug manufacturers.
Sep 2, 2007
By: Patrick Okoye, Stephen H. Wu
Pharmaceutical Technology

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22. A. El Hagrasy, S. Chang, and T. Hu, "Evaluation of Risk and Benefit in the Implementation of Near-Infrared Spectroscopy for Monitoring of Lubricant Mixing," J. Pharm. Dev. Technol. 11 (3), 303–312 (2006).

23. V. Swaminathan, D. Simmons, and M. Bourland, "Effect of Magnesium Stearate on Ribbon, Granule and Tablet Characteristics in Dry Granulation," AAPS abstract T2212 (2006).

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About the Author

Patrick Okoye

Patrick Okoye is in the quality department at OSG/Kolmar Laboratories, Inc. Articles by Patrick Okoye

Stephen H. Wu


Stephen H. Wu, PhD, is a technical fellow in the Pharmaceutical R&D division of Mallinckrodt PharmaceuticalCovidien Ltd. Articles by Stephen H. Wu
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Source: Pharmaceutical Technology, 9/2/2007
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