Simulated Moving Bed Chromatography: A Powerful Unit Operation - Pharmaceutical Technology

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Simulated Moving Bed Chromatography: A Powerful Unit Operation
High performance liquid chromatography has become an efficient technique at the production scale, and simulated moving bed chromatography provides several benefits during processing.


Pharmaceutical Technology


Conclusion

Because it provides high purity, high yields, and potentially high throughput, chromatography is the ultimate purification technique. With recent improvements in technology and stationary phases, the cost of using chromatography has significantly decreased, making this unit operation a very cost effective and commercially viable technology.

For a related article, see In the Loop: Continuous Chromatography for Chiral (and Other) Separations.

Olivier Dapremont, PhD, is director of chromatography business development at AMPAC Fine Chemicals, PO Box 1718, MS 1007, Rancho Cordova, CA 95741-1718, tel. 916.357.6242, fax 916.353.3523,
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