The Disintegration and Dissolution of Nabumetone Dispersible Tablets - Pharmaceutical Technology

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The Disintegration and Dissolution of Nabumetone Dispersible Tablets
Nabumetone was complexed with β-cyclodextrin, and a 23 factorial design was used to prepare dispersible tablets containing the drug or its complex.The authors analyzed the effects of complexation as well as the levels of ammonium bicarbonate and crospovidone on tablet wetting time (WT), disintegration time (DT), and percent dissolution efficiency at 60 min (%DE60).


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25. K. Kiozumi et al., "New Method of Preparing High-Porosity Rapidly Saliva Soluble Compressed Tablets using Mannitol with Camphor, a Subliming Material," Int. J. Pharm. 152, 127 –131 (1997).

26. D.M. Patel, "Studies in Formulation of Orodispersible Tablets of Rofecoxib," Ind. J. Pharm. Sci. 66, 621–625 (2004). PT


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