What's Next In: Ingredients - Pharmaceutical Technology

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What's Next In: Ingredients

Pharmaceutical Technology

5. S.S. Zhu et al., "Chiral Mo-Binol Complexes: Activity, Synthesis, and Structure. Efficient Enantioselective Six-Membered Ring Synthesis through Catalytic Metathesis," J. Am. Chem. Soc. 121 (36), 8251-8259 (1999).

6. R.R. Schrock and A.H. Hoveyda, "Molybdenum and Tungsten Imido Alkylidene Complexes as Efficient Olefin-Metathesis Catalysts," Angew. Chem., Int. Ed. 42 (38), 4592-4633 (2003).

7. A.H. Hoveyda and R.R. Schrock, "Catalytic Asymmetric Olefin Metathesis," Chem. Eur. J. 7 (5 ), 945-950 (2001).

8. T.J. Seiders, D.W. Ward, and R.H. Grubbs, "Enantioselective Ruthenium-Catalyzed Ring-Closing Metathesis," Org. Lett. 3 (20) 3225-3228 (2001).

9. J.J. Van Veldhuizen. "A Recyclable Chiral Ru Catalyst for Enantioselective Olefin Metathesis. Efficient Catalytic Asymmetric Ring-Opening/Cross Metathesis in Air," J. Am. Chem. Soc. 124 (18), 4954-4955 (2002).

10. J.J. Van Veldhuizen et al., "Chiral Ru-Based Complexes for Asymmetric Olefin Metathesis: Enhancement of Catalyst Activity through Steric and Electronic Modification," J. Am. Chem. Soc. 125 (41), 12502-12508 (2003).

11. D.G. Gillingham et al., "Efficient Enantioselective Synthesis of Functionalized Tetrahydropyrans by Ru-Catalyzed Asymmetric Ring-Opening Metathesis/Cross-Metathesis (AROM/CM)," J. Am. Chem. Soc. 126 (6), 12288-12290 (2004).

12. T.W. Funk, J.M. Berlin, and R.H. Grubbs, "A Highly Active Palladium Catalyst for Intermolecular Hydroamination. Factors that Control Reactivity and Additions of Functionalized Anilines to Dienes and Vinylarenes," J. Am. Chem. Soc. 128 (6), 1840-1846 (2006).

Industry experts give their predictions for the next 30 years. Read Editor-in-Chief Michelle Hoffman's introduction here. See what's next in:

Strategy and Regulation
Solid-Dosage Formulation
Drug Delivery
Analytical Testing
Information Technology


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View Results
Eric Langer Outsourcing Outlook Eric LangerBiopharma Outsourcing Activities Update
Cynthia Challener, PhD Ingredients Insider Cynthia Challener, PhDAppropriate Process Design Critical for Commercial Manufacture of Highly Potent APIs
Jill Wechsler Regulatory Watch Jill Wechsler FDA and Manufacturers Seek a More Secure Drug Supply Chain
Sean Milmo European Regulatory WatchSean MilmoQuality by Design?Bridging the Gap between Concept and Implementation
Report: Pfizer Makes $101 Billion Offer to AstraZeneca
Medicare Payment Data Raises Questions About Drug Costs
FDA Wants You!
A New Strategy to Tackle Antibiotic Resistance
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Source: Pharmaceutical Technology,
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