Cocktail-Solvent Screening to Enhance Solubility, Increase Crystal Yield, and Induce Polymorphs - Pharmaceutical Technology

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Cocktail-Solvent Screening to Enhance Solubility, Increase Crystal Yield, and Induce Polymorphs
The authors propose extending initial solvent screening for a single-solvent system to the cocktail solvent screening of binary and ternary solvent mixtures.

Pharmaceutical Technology
Volume 32, Issue 1


Figure 11
This work was supported by a grant from the National Science Council of Taiwan (NSC 93-2113-M-008-012-MY2). Suggestions from Ms. Jui-Mei Huang of the National Central University Precision Instrument Center regarding DSC and TGA are gratefully acknowledged.

Tu Lee is an assistant professor and Shi Ting Hung was a graduate student in the Department of Chemical and Materials Engineering and the Institute of Materials Science and Engineering, National Central University, 300 Jhong-Da Rd., Jhong-Li City 320, Taiwan, China, tel. 1886 3 422 7151 ext. 34204, fax 1886 3 425 2296,

*To whom all correspondence should be addressed.

Submitted: Mar. 26, 2007. Accepted: Apr. 27, 2007.


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