Assessing Hibiscus rosa-sinensis Linn as an Excipient in Sustained-Release Tablets - Pharmaceutical Technology

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Assessing Hibiscus rosa-sinensis Linn as an Excipient in Sustained-Release Tablets
Natural gums and mucilage are biocompatible, cheap, readily available, and represent a potential source of excipients. The authors examine the functionality of mucilage extracted from the leaves of Hibiscus rosa-sinensis Linn as an excipient in a sustained-release tablet formulation.


Pharmaceutical Technology
Volume 32, Issue 1

15. P. Santiago et al. "Design of Peumus boldus Tablets by Direct Compression Using a Novel Dry Plant Extract," Int. J. Pharm. 233 (1–2), 191–198 (2002).

16. C.W. Vendruscolo et al, "Xanthan and Galactomannan (from M. scabrella) Matrix Tablets for Oral Controlled Delivery of Theophylline," Int. J. Pharm. 296 (1–2), 1–11 (2005).

17. F. Ughini et al., "Evaluation of Xanthan and Highly Substituted Galactomannan from M. scabrella as a Sustained Release Matrix," Int. J. Pharm. 271 (1–2), 197–205 (2004).

18. U. Melike and A. Turan, "Evaluation of Honey Locust (Gleditsia triacanthos Linn) Gum as a Sustaining Material in Tablet Dosage Form," IL Farmaco 59 (7), 567–573 (2004).

19. P.D. Bharadia et al., "A Preliminary Investigation on Sesbania Gum as a Pharmaceutical Excipient," Int. J. Pharma. Excip. 1 (4) 99–102 (2004).

20. S.K. Baveja, K.V. Rao, and J. Arora, "Examination of Natural Gums and Mucilage as Sustaining Agents in Tablet Dosage Forms," Indian J. Pharm. Sci. 50 (2), 89–92 (1988).

21. S. Sumathi and A.R. Ray, "Release Behavior of Drugs from Tamarind Seed Polysaccharide Tablets," J. Pharm. Sci. 5 (1), 12–18 (2002).

22. D.M. Morkhade et al., "Gum Copal and Gum Damar: Novel Matrix Forming Material for Sustained Drug Delivery," Ind. J. Pharm. Sci. 68 (1), 53–58 (2006).

23. J. Anjaria, M. Parabia, and S. Dwivedi, Ethnovet Heritage–Indian Ethnoveterinary Medicine an Overview. (Pathik Enterprise, Ahmedabad, India, 1st ed., 2002), p. 382.

24. I.A. Ross, Medicinal Plants of the World—Chemical Constituents, Traditional and Modern Medicine Uses (Humana Press, Totowa, NJ 1999), pp. 155-163.

25. K.R. Kirtikar and B. D. Basu, Indian Medicinal Plants (International Book Distributors, Dehradun, India, 1999), p. 335.

26. The Wealth of India, First Supplement Series (Raw Materials) (National Institute of Science and Communication, CSIR, New Delhi, India, Volume 3: D–I, 2002), pp. 386–387.

27. The Wealth of India, First Supplement Series (Raw Materials) (National Institute of Science and Communication, CSIR, New Delhi, India, Volume V: H–K, 2002), pp. 91–92.

28. J.A. Duke, and E. S. Ayensu, Medicinal Plants of China. (Reference Publication Inc., Algonac, MI 1985).

29. J.G. Hardman and L.E. Limbrid. Goodman's and Gilman's The Pharmacological Basis of Therapeutics (McGraw Hill, New York, 9th ed., 1995).


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