Variables Affecting Reconstitution Time of Dry Powder for Injection - Pharmaceutical Technology

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Variables Affecting Reconstitution Time of Dry Powder for Injection
The authors describe the factors affecting reconstitution time of dry powder for injection and classifies them as intrinsic and extrinsic parameters.


Pharmaceutical Technology


References

1. "‹1› Injections" in USP 29–NF 24 (United States Pharmacopeial Convention, Rockville, MD, 2006), pp. 2455–2458.

2. International Conference on Harmonization, Q6A: Specifications: Test Procedures and Acceptance Criteria For New Drug Substances and New Drug Products:Chemical Substances (ICH, Geneva, Switzerland, 2003).

3. "Amifostine for Injection" in USP 29–NF 24 (United States Pharmacopeial Convention, Rockville, MD, 2006), p. 126.

4. "Haemosolvate Factor VIII (Powder for Injection)," package insert (Pinetown, South Africa), http://www.home.intekom.com/pharm/nbi/viii1000.html, accessed May 11, 2007.

5. S. Redkar and P. Phiasivongsa, "Salts of 5-Azacytidine," US Patent 2006/0063735 A1 (2006).

6. A.A. Noyes and W.R. Whitney, "The Rate of Solution of Solid Substances in Their Own Solutions," J. Am. Chem. Soc. 19 (12), 930–934 (1897).

7. M. Melgardt, "Influence of Agglomeration of Cohesive Particles on the Dissolution Behaviour of Furosemide Powder," Int. J. Pharm. 136, 175–179 (1996).

8. P.K. Hla and S. Hogekamp, "Wetting Behaviour of Instantized Cocoa Beverage Powders," Int. J. Food Sci. Technol. 34, 335–342 (1999).

9. W. Wu and G.H. Nancollas, "Determination of Interfacial Tension from Crystallization and Dissolution Data: A Comparison with Other Methods," Adv. Colloid Interface Sci. 79 (2–3), 229–279 (1999).

10. H.E. Bruce, "Composition of Matter Comprising a Lyophilized Preparation of a Penicillin Derivative," US Patent 4477452 (1984).

11. L. Moscou and S. Lub, "Practical Use of Mercury Porosimetry in the Study of Porous Solids," Powder Technol. 29 (1), 45–52 (1981).

12. S. Westermarck et al., "Mercury Porosimetry of Pharmaceutical Powders and Granules," J. Porous Mater. 5 (1), 77–86 (1998).

13. P.J. Dees and J. Polderman, "Mercury Porosimetry in Pharmaceutical Technology," Powder Technol. 29 (1), 187–197 (1981).

14. S. Westermarck et al., "Pore Structure and Surface Area of Mannitol Powder, Granules and Tablets Determined with Mercury Porosimetry and Nitrogen Adsorption," Eur. J. Pharm. Biopharm. 46 (1), 61–68 (1998).

15. S. Brunauer et al., "Adsorption of Gases in Multimolecular Layers," J. Am. Chem. Soc. 60 (2), 309–319 (1938).

16. L. Farber et al., "Use of X-ray Tomography to Study the Porosity and Morphology of Granules," Powder Technol. 132 (1), 57–63 (2003).


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