Conclusion
The methods of active pharmaceutical ingredient in a capsule, drug in a bottle, liquid in a capsule, or multiple binary blends
provide options for getting drug product into the clinic in a short period of time. Although not all the options are capable
of reaching commercial scale, they are all capable of supporting early clinical studies and may be used as a path to an eventual
commercial dosage form.
Acknowledgment
The author is thankful to Paul Skultety, director of pharmaceutical development services at Xcelience for final review.
Balaji V. Kadri is a manager of the preformulation and formulation-development department at Xcelience, 5415 West Laurel St., Tampa, FL 33647,
tel. 813.286.0404, fax 813.286.1105, balaji.kadri@xcelience.com
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