Formulation Development of Taste-Masked Rapidly Dissolving Films of Cetirizine Hydrochloride - Pharmaceutical Technology

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Formulation Development of Taste-Masked Rapidly Dissolving Films of Cetirizine Hydrochloride
The authors formulated and developed taste-masked RDFs of cetirizine hydrochloride for patients who experience difficultly in swallowing the tablet dosage form of the drug.

Pharmaceutical Technology
Volume 33, Issue 2, pp. 48-56


1. A.C. Liang and L.H. Chen, "Fast Dissolving Intraoral Drug Delivery Systems," Exp. Opin. Ther. Patents 11 (6), 981–986 (2001).

2. S. Borsadia, D. O'Halloran, and J.L. Osborne, "Quick Dissolving Films: A Novel Approach to Drug Delivery," Drug Del. Technol., 3 (3), 84–90(2003).

3. J. Klanke, "Dissolution Testing of Orally Disintegrating Tablets," Dissol. Technol., 10 (2), 6–8 (2003).

4. S.R. Parakh and A.V. Gothoskar, "A Review of Mouth Dissolving Tablet Technologies," Pharm. Technol., 27 (11), 92–100 (2003).

5. "Novartis Launches First Systemic OTC in Film Strip Format," available at accessed on Feb. 4, 2008.

6. "Pharmacist Counselling Can Prevent Unintentional Errors with Thin Strip Dosage Forms," available at, accessed on Feb. 4, 2008

7. P. Van Arnum, "Outsourcing Solid Dosage Manufacturing," Pharm. Technol., 30 (6), 44–52 (2006).

8. "Intraoral Delivery Systems: An Overview, Current Status, and Future Trends," in Drug Delivery to the Oral Cavity: Molecules to Market, T. Ghosh and W. Pfister, Eds. (CRC Press, Taylor & Francis Group, FL, vol. 145, 2005), pp. 1–34.

9. C.M.Corniello, "Quick-Dissolving Strips: From Concept to Commercialization," Drug Del. Technol. 6 (2), 68–71 (2006).

10. R. Mishra and A. Amin, "Quick API Delivery," Pharm. Technol. Europe 19 (10), 35–39 (2007).

11 . R.C. Mashru et al., "Development and Evaluation of Fast Dissolving Film of Salbutamol Sulphate," Drug Dev. Ind. Pharm., 31 (1), 25–34 (2005).

12. Drug Card for Cetirizine, available at, accessed on Apr. 14, 2008.

13. Zyrtec information, available at, accessed on Apr. 12, 2008.

14. R. Agarwal, R.Mittal, and A.Singh, "Studies of Ion-Exchange Resin Complex of Chloroquine Phosphate," Drug Dev. Ind. Pharm., 26 (7), 773–776 (2000).


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