The Rotation of Disinfectants Principle: True or False? - Pharmaceutical Technology

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PharmTech Europe

The Rotation of Disinfectants Principle: True or False?
The author defines sanitizers, disinfectants, and antibiotics, and examines the question of whether the rotation of disinfectants is scientifically warranted.


Pharmaceutical Technology
Volume 33, Issue 2, pp. 58-71

5. J.E. Martínez, "Mode of Action and Development of Resistance to Disinfectants, Part 1," Bioprocess Int. 3 (8), 32–38 (2005).

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7. S.L. Hazell et al., "Resistance to Hydrogen Peroxide in Helicobacter pylori : Role of Catalase (KatA) and Fur, and Functional Analysis of a Novel Gene Product Designated 'KatA-Associated Protein', KapA (HP0874)," Microbiology 148, 3813–3825 (2002).

8. O.M. Hartford and B.C. Dowds, "Isolation and Characterization of a Hydrogen Peroxide Resistant Mutant of Bacillus subtilis ," Microbiology 140, 297–304 (1994).

9. T.R. McDermott et al., "Protective Role of Catalase in Pseudomonas aeruginosa Biofilm Resistance to Hydrogen Peroxide," Appl. Environ. Microbiol. 65 (10), 4594–4600 (1999).

10. M.W. LeChevallier, C.D. Cawthon, and R.G. Lee, "Inactivation of Biofilm Bacteria," Appl. Environ. Microbiol. 54, 2492–2499 (1988).

11. P.S. Stewart and X. Chen, "Chlorine Penetration into Artificial Biofilm is Limited by a Reaction–Diffusion Interaction," Environ. Sci. Technol. 30 (6), 2078–2083 (1996).

12. Centers for Disease Control, "Contaminated Povidone Iodine Solution-Texas," MMWR Morb. Mortal. Wkly. Rep. 38, 133–134 (1989).

13. B. Demple and L. Harrison, "Repair of Oxidative Damage to DNA: Enzymology and Biology," Annu. Rev. Biochem. 63, 915–948 (1994).

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15. P.M. Kaulfers, N. Kümmerle, and H.H. Feucht, "Plasmid-Mediated Formaldehyde Resistance in Escherichia coli : Characterization of Resistance Gene," Antimicrob. Agents Chemother. 40 (10), 2276–2279 (1996).

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