The Rotation of Disinfectants Principle: True or False? - Pharmaceutical Technology

Latest Issue
PharmTech

Latest Issue
PharmTech Europe

The Rotation of Disinfectants Principle: True or False?
The author defines sanitizers, disinfectants, and antibiotics, and examines the question of whether the rotation of disinfectants is scientifically warranted.


Pharmaceutical Technology
Volume 33, Issue 2, pp. 58-71

46. G. Mayer, "Antibiotics that Affect the Cell Envelope" in Microbiology and Immunology, University of South Carolina, http://pathmicro.med.sc.edu/mayer/antibiot.htm, accessed Jan. 18, 2009.

47. T. Montie and P. Patamasucon. "Aminoglycosides: the Complex Problem of Antibiotic Mechanisms and Clinical Applications," Eur. J. Clin. Microbiol. Infect. Dis. 14, 85–87 (1995).

48. H.J. Busse, C. Wostmann, and E.P. Bakker, "The Bactericidal Action of Streptomycin: Membrane Permeabilization Caused by the Insertion of Mistranslated Proteins into the Cytoplasmic Membrane of Escherichia coli and Subsequent Caging of the Antibiotic inside the Cells: Degradation of these Proteins," J. Gen. Microbiol. 138, 551–561 (1992).

49. H.F. Chambers and M.A. Sande, "Antimicrobial Agents: The Aminoglycosides," in The Pharmacological Basis of Therapeutics, J.G. Hardman et al., Eds. (McGraw-Hill, New York, 1995), pp. 1103–1121.

50. J. Davies and G. Wright, "Bacterial Resistance to Aminoglycoside Antibiotics," Trends Microbiol. 5, 234–239 (1997).

51. K.J. Shaw et al., "Molecular Genetics of Aminoglycoside Resistance Genes and Familial Relationships of the Aminoglycoside-Modifying Enzymes," Microbiol. Rev. 57, 138–163 (1993).

52. E.K. Manavathu et al., "Molecular Studies on the Mechanism of Tetracycline Resistance Mediated by Tet(O)," Antimicrob. Agents Chemother. 34, 71–77 (1990).

53. S.B. Levy et al., "Nomenclature for New Tetracycline Resistance Determinants," Antimicrob. Agents Chemother. 43, 1523–1524 (1999).

54. I. Chopra, "New Developments in Tetracycline Antibiotics: Glycylcyclines and Tetracycline Efflux Pump Inhibitors," Drug Resist. Updat. 5 (3–4), 119–125 (2002).

55. M.C. Roberts, "Tetracycline Resistant Determinants: Mechanisms of Action, Regulation of Expression, Genetic Mobility, and Distribution," FEMS Microbiol. Rev. 19, 1–24 (1996).

56. F. Schluenzen et al. "Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Centre in Eubacteria", Nature 413, 814–821 (2001).

57. R. Fernandez-Muñoz and D. Vazquez, "Kinetic Studies of Peptide Bond Formation: Effect of Chloramphenicol," Mol. Biol. Rep. 1, 75–79 (1973).

58. M. Michelinaki et al., "Aminoacyl and Peptidyl Analogs of Chloramphenicol as Slow-Binding Inhibitors of Ribosomal Peptidyltransferase: A New Approach for Evaluating Their Potency," Mol. Pharmacol. 51, 139–146 (1997).

59. M.A. Xaplanteri et al., "Effect of Polyamines on the Inhibition of Peptidyltransferase by Antibiotics: Revisiting the Mechanism of Chloramphenicol Action," Nucleic Acids Res. 31, 5074–5083 (2003).


ADVERTISEMENT

blog comments powered by Disqus
LCGC E-mail Newsletters

Subscribe: Click to learn more about the newsletter
| Weekly
| Monthly
|Monthly
| Weekly

Survey
What is the single greatest threat to maintaining manufacturing processes at your facility?
Quality issues
Facility/environment problems
Process development problems
Production equipment downtime
Raw material supply problems
Regulatory restrictions
Business decisions to limit production
Quality issues
44%
Facility/environment problems
0%
Process development problems
11%
Production equipment downtime
11%
Raw material supply problems
11%
Regulatory restrictions
0%
Business decisions to limit production
22%
View Results
UPCOMING CONFERENCES

Programs for Investigational and Pre-Launch Drugs
Philadelphia, PA
July 17-18, 2013
Request Brochure

Strategic Pipeline Planning & Portfolio Valuation
Philadelphia, PA
August 13-14, 2013
Request Brochure

MES 2013 - Forum on Manufacturing Execution Systems
Philadelphia, PA
August 14-15, 2013
Request Brochure

Mobile Innovation for the Life Sciences Industry
Philadelphia, PA
August 20-21, 2013
Request Brochure

See All Conferences >>

Eric Langer Outsourcing Outlook Eric LangerOutsourcing's Modest Role as a Cost-Containment Strategy
Patricia Van Arnum Ingredients Insider Patricia Van ArnumIntellectual Property Battles in Solid-State Chemistry
Nathan Jessop Industry Insider Nathan Jessop Campaign Against Counterfeit Drugs Continues
Lynn Torbeck Statistical Solutions Lynn D. TorbeckCompositing Samples and the Risk to Product Quality
 More
Patent Settlements Become More Risky
Praise and Perils for Biotechnology Patent Policy
Risk-Mitigation Strategies in Drug Manufacturing for Emerging Markets
Quality Focus: Ensuring Raw Material Transparency
Advertising of Prescription Drugs  Keeping it Honest and Balanced
Source: Pharmaceutical Technology,
Click here