The Rotation of Disinfectants Principle: True or False? - Pharmaceutical Technology

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The Rotation of Disinfectants Principle: True or False?
The author defines sanitizers, disinfectants, and antibiotics, and examines the question of whether the rotation of disinfectants is scientifically warranted.

Pharmaceutical Technology
Volume 33, Issue 2, pp. 58-71

60. D.G. White et al., "Characterization of Chloramphenicol and Florfenicol Resistance in Escherichia coli Associated with Bovine Diarrhea," J. Clin. Microbiol. 38 (12), 4593–4598 (2000).

61. B. Weisblum, "Insights into Erythromycin Action from Studies of its Activity as Inducer of Resistance," Antimicrob Agents Chemother. 39, 797–805 (1995).

62. B. Weisblum, "Erythromycin Resistance by Ribosome Modification," Antimicrob Agents Chemother. 39, 577–585 (1995).

63. J. Kataja, P. Huovinen, and H. Seppala, "Erythromycin Resistance Genes in Group A Streptococci of Different Geographical Origins: the Macrolide Resistance Study Group," J. Antimicrob. Chemother. 46, 789–792 (2000).

64. W. Godtfredsen, K. Roholt, and L. Tybring, "Fucidin: A New Orally Active Antibiotic," Lancet, 928–931 (1962).

65. L. Verbist, "The Antimicrobial Activity of Fusidic Acid," J. Antimicrob. Chemother. 25 (Suppl. B), 1–5 (1990).

66. J.W. Bodley et al., "Studies on Translocation: Conditions Necessary for the Formation and Detection of a Stable Ribosome-G Factor-Guanosine Diphosphate Complex in the Presence of Fusidic Acid," J. Biol. Chem. 245 (21), 5656–5661 (1970).

67. I. Chopra, "Mechanisms of Resistance to Fusidic Acid in Staphylococcus aureus, " J. Gen. Microbiol. 96, 229–238 (1976).

68. H. Schrempf and B. Von Der Haar, "Purification and Characterization of a Novel Extracellular Enzyme Inactivating Fusidic Acid," J. Bacteriol. 177 (1), 152–155 (1995).

69. W.R. McClure and C.L. Cech, "On the Mechanism of Rifampicin Inhibition of RNA Synthesis," J. Biol. Chem. 253, 8949–8956 (1978).

70. M.P. Cummings and M.R. Segal. "Few Amino Acid Positions in rpoB Are Associated with Most of the Rifampin Resistance in Mycobacterium tuberculosis, " BMC Bioinformatics 5, 137 (2004), available at accessed Jan. 18, 2009.

71. Z. Saribas et al., "Rapid Detection of Rifampin Resistance in Mycobacterium tuberculosis Isolates by Heteroduplex Analysis and Determination of Rifamycin Cross-Resistance in Rifampin-Resistant Isolates," J. Clin. Microbiol. 41, 816–818 (2003).

72. G.Y. Lesher et al., "1, 8-Naphthynidine Derivatives: A New Class of Chemotherapeutic Agents," J. Med. Pharm. Chem. 5, 1063–1068 (1962).

73. R.C. Owens Jr. and P.G. Ambrose, "Clinical Use of the Fluoroquinolones," Med. Clin. North Am. 84, 1447–1469 (2000).

74. D.C. Hooper, "New Uses for New and Old Quinolones and the Challenge of Resistance," Clin. Infect. Dis. 30, 243–254 (2000).


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