The Rotation of Disinfectants Principle: True or False? - Pharmaceutical Technology

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PharmTech Europe

The Rotation of Disinfectants Principle: True or False?
The author defines sanitizers, disinfectants, and antibiotics, and examines the question of whether the rotation of disinfectants is scientifically warranted.


Pharmaceutical Technology
Volume 33, Issue 2, pp. 58-71

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92. T. Köhler et al., "Multidrug Efflux in Intrinsic Resistance to Trimethoprim and Sulfamethoxazole in Pseudomonas aeruginosa, " Antimicrob. Agents Chemother. 40 (10), 2288–2290 (1996).

93. S.G.B. Amyes et al., "The Type VII Dihydrofolate Reductase: A Novel Plasmid-Encoded Trimethoprim-Resistant Enzyme from Gram-Negative Bacteria Isolated in Britain," J. Antimicrob. Chemother. 24, 111–119 (1989).

94. B.A. Wylie et al., "Identification of a Novel Plasmid-Encoded Dihydrofolate Reductase Mediating High Level Resistance to Trimethoprim," J. Antimicrob. Chemother. 22, 429–435 (1988).

95. R.L. Then, "Mechanisms of Resistance to Trimethoprim, the Sulfonamides, and Trimethoprim-Sulphamethoxazole," Rev. Infect. Dis. 4, 261–269 (1982).

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