The Rotation of Disinfectants Principle: True or False? - Pharmaceutical Technology

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PharmTech Europe

The Rotation of Disinfectants Principle: True or False?
The author defines sanitizers, disinfectants, and antibiotics, and examines the question of whether the rotation of disinfectants is scientifically warranted.


Pharmaceutical Technology
Volume 33, Issue 2, pp. 58-71

103. H.E. Morton, "The Relationship of Concentration and Germicidal Efficiency of Ethyl Alcohol," Ann. N.Y Acad. Sci. 53, 191–196 (1950).

104. C.E. Coulthard and G. Sykes, "The Germicidal Effect of Alcohol with Special Reference to its Action on Bacterial Spores," Pharm. J. 137, 79–8l (1936).

105. C.R. Smith, "Alcohol as a Disinfectant against the Tubercle Bacillus," Public Health Report 62, 1285–1295 (1947).

106. J.M. Tennent et al., "Cloning and Expression of Staphylococcus aureus Plasmid-Mediated Quaternary Ammonium Resistance in Escherichia coli, " Antimicrob. Agents Chemother. 27 (1), 79–83 (1985).

107. M.S. To et al., "Postadaptational Resistance to Benzalkonium Chloride and Subsequent Physicochemical Modifications of Listeria monocytogenes, " Appl. Environ. Microbiol. 68 (11), 5258–5264 (2002).

108. M. Sondossi and H.W. Rossmoore, "Applications and Mode of Action of Formaldehyde Condensate Biocides," Adv. Appl. Microbiol. 33, 223–277 (1988).

109. M.S. Favero and W.W. Bond, "Chemical Disinfection of Medical and Surgical Materials,"in Disinfection, S.S. Block, Ed. (Lea and Febiger, Philadelphia, 4th ed., 1991), pp. 617–641.


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