Initial Solvent Screening of Carbamazepine, Cimetidine, and Phenylbutazone: Part 2 of 2 - Pharmaceutical Technology

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Initial Solvent Screening of Carbamazepine, Cimetidine, and Phenylbutazone: Part 2 of 2
The authors describe the importance of a rapid and an abbreviated screening strategy in initial solvent screening. This article contains bonus online-exclusive material.


Pharmaceutical Technology
Volume 33, Issue 6

References

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4. B. Hegedüs and S. Görög, "The Polymorphism of Cimetidine," J. Pharm. Biomed. Anal. 3 (4), 303–313 (1985).

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9. T. Lee and S.T. Hung, "Cocktail-Solvent Screening to Enhance Solubility, Increase Crystal Yield, and Induce Polymorphs," Pharm. Technol. 32 (1), 76–95 (2008).

10. C.C. Chen and P.A. Crafts, "Correlation and Prediction of Drug Molecule Solubility in Mixed Solvent Systems with the Nonrandom Two-Liquid Segment Activity Coefficient (NRTL-SAC) Model," Ind. Eng. Chem. Res. 45 (13), 4816–4824 (2006).

11. A. Getsoian, R.M. Lodaya, and A.C. Blackburn, "One-Solvent Polymorph Screen of Carbamazepine," Int. J. Pharm. 348 (1–2), 3–9 (2008).

12. T. Lee, Y.H. Chen, and C.W. Zhang, "Solubility, Polymorphism, Crystallinity, Crystal Habit, and Drying Scheme of (R,S)-(±)-Sodium Ibuprofen Dihydrate," Pharm. Technol. 31 (6), 72–87 (2007).

13. C. Rey-Mermet et al., "Significance of Partial and Total Cohesion Parameters of Pharmaceutical Solids Determined from Dissolution Calorimetric Measurements," Pharm. Res. 8 (5), 636–642 (1991)."

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15. T. Hosokawa et al., "Relationships between Crystal Structures and Thermodynamic Properties of Phenylbutazone Solvates," Cryst. Eng. Comm. 6 (44), 243–249 (2004).

16. T. Lee and M.S. Lin, "Sublimation Point Depression of Tris(8-hydroxyquinoline)aluminum(III) (Alq3) by Crystal Engineering," Cryst. Growth Des. 7 (9), 1803–1810 (2007).

17. Y. Kobayashi et al., "Physicochemical Properties and Bioavailability of Carbamazepine Polymorphs and Dihydrate," Int. J. Pharm. 193 (2), 137–146 (2000).

18. R. Hilfiker et al., "Polymorphism—Integrated Approach from High-Throughput Screening to Crystallization Optimization," J. Therm. Anal. Calorim. 73 (2) 429–440 (2003).

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