Engineering Processing Properties of Acetaminophen by Cosolvent Screening - Pharmaceutical Technology

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Engineering Processing Properties of Acetaminophen by Cosolvent Screening
The authors used common solvents to develop an initial solvent-screening method for laboratory-scale research to determine the solubility, polymorphism, and crystal properties of various active ingredients.


Pharmaceutical Technology
Volume 34, Issue 8, pp. 61-68

9. T. Lee and M.S. Lin, Cryst. Growth Des. 7 (9), 1803–1810 (2007).

10. T. Lee and S.T. Hung, Pharm. Technol. 32 (1), 76–95 (2008).

11. T. Lee, S.T. Hung, and C.S. Kuo, Pharm. Res. 23 (11), 2542–2555 (2006).

12. J.C. Burley et al., Eur. J. Pharm. Sci. 31 (5), 271–276 (2007).

13. N. Al-Zoubi, K. Kachrimanis, and S. Malamataris, Eur. J. Pharm. Sci. 17 (1–2), 13–21 (2002).

14. N. Al-Zoubi and S. Malamataris, Int. J. Pharm., 260 (1), 123–135 (2003).

15. P. Di Martino et al., J. Therm. Anal. 48 (3), 447–458 (1997).

16. M. L. Ramos, J.F. Tyson, and D.J. Curran, Anal. Chim. Acta 364 (1–3), 107–116 (1998).

17. R.G. Hollenbeck, J. Pharm. Sci. 69 (10), 1241–1242 (1980).

18. J.W. Mullin, "Solutions and Solubility," in Crystallization, (Butterworth Heinemann, Oxford, UK, 3rd ed., 1992), pp. 93–94.

19. S.H. Yalkowsky, "Solubilization by Cosolvents," in Solubility and Solubilization in Aqueous Media, (American Chemical Society and Oxford University Press, New York, 1999), pp. 180–235.

20. P.W.S. Heng and L.W. Chan, "Drug Substance and Excipient Characterization," in Handbook of Pharmaceutical Granulation Technology, D. M. Parikh, Ed. (Marcel Dekker, New York, 1st ed., 1997), p. 28.

21. M. Kitamura, M. Sugimoto, J. Cryst. Growth 257 (1–2), 177–184 (2003).

22. M. Lahav and L. Leiserowitz, Chem. Eng. Sci. 56 (7), 2245–2253 (2001).

23. B.F. Ruth, Ind. Eng. Chem. Res. 38 (6), 564–571 (1946).

24. E.W. Comings and T.K. Sherwood, Ind. Eng. Chem. Res. 26 (10), 1096–1098 (1934).

25. K. Miyanami, "Mixing," in Powder Technology Handbook, K. Gotoh, H. Masuda, and K. Higashitani, Eds. (Marcel Dekker, New York, 2nd ed., 1997), p. 618.

26. K. Umeya and I. Sekiguchi, J. Soc. Mater. Sci. Japan. 24 (262), 664–668 (1975).

27. B.E. Kurtz and A.J. Barduhn, Chem. Eng. Prog. 56 (1), 67–72 (1960).

28. T. Lee and C.S. Kuo, Pharm. Technol. 30 (3), 110–120 (2006).

29. W. Nernst, Z. Physik. Chem. 47 (1), 52–55 (1904).

30. E. Brunner, Z. Physik. Chem. 47 (1), 56–102 (1904).


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